Citation: Yan-Hui Dou, Hai-Xin Ding, Ru-Chun Yang, Wei Li, Qiang Xiao. A total synthesis of mycalisine A[J]. Chinese Chemical Letters, ;2013, 24(05): 379-382. shu

A total synthesis of mycalisine A

1.
Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang 330013, China

Corresponding author: Qiang Xiao,
Received Date: 26 November 2012
Available Online: 27 February 2013

In this paper, we report a total synthesis of a naturally occurring pyrrolo[2,3-d]pyrimidine nucleoside, mycalisine A. Our synthetic strategy uses D-xylose as the startingmaterial and Vorbrüggen glycosylation as the key step. Mycalisine A was synthesized in 11 steps with a 15% overall yield.
- Naturally occurring nucleoside,
- Total synthesis,
- Vorbrüggen glycosylation,
- Mycalisines A,
- Pyrrolo[2,3-d]pyrimidine
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沈阳化工大学材料科学与工程学院沈阳 110142