Citation: Zhongzhe Wei, Fangjun Shao, Jianguo Wang. Recent advances in heterogeneous catalytic hydrogenation and dehydrogenation of N-heterocycles[J]. Chinese Journal of Catalysis, ;2019, 40(7): 980-1002. doi: S1872-2067(19)63336-X shu

Recent advances in heterogeneous catalytic hydrogenation and dehydrogenation of N-heterocycles

Institute of Industrial Catalysis, College of Chemical Engineering, State Key Laboratory Breeding Base of Green-Chemical Synthesis Technology, Zhejiang University of Technology, Hangzhou 310032, Zhejiang, China

Received Date: 31 December 2018
Revised Date: 2 February 2019

Fund Project: This work was supported by the National Postdoctoral Innovative Talent Support Program (Z86101001), China Postdoctoral Science Foundation (Z741010006), and Preferred Postdoctoral Research Projects Foundation of Zhejiang Province (Z87101003).

The selective hydrogenation of quinolines to 1,2,3,4-tetrahydroquinolines (py-THQ) and its derivatives has attracted a considerable amount of attention as they show great versatility in many pharmaceuticals, agrochemicals, and fine chemicals. Over the past few decades, great breakthroughs have been achieved in the controlled synthesis of efficient heterogeneous catalysts used for the selective hydrogenation of functionalized quinoline compounds, which allow one to correlate the structure-property relationships. In this review, we will summarize the recent significant progress achieved in this field covering the synthetic strategies, microstructural and chemical features, catalytic performance, and internal relationships. State-of-the-art noble metal-based single (Pd, Pt, Ru, Rh, Ir and Au) and bi/multi-metallic catalysts (RuCu, AuPd, and PdNi) are first introduced, followed by a summary of earth-abundant metal-based catalysts (Co, Fe, Ni, and Cu). Finally, the dehydrogenation of N-heterocycles is introduced to form a reversible hydrogenation/dehydrogenation system for H₂ storage, which can be employed in a liquid organic hydrogen system. Furthermore, the reaction mechanism and future research direction in these areas are also discussed. This review will deepen our understanding of the catalytic transformation of N-heterocycles and provide guidance for researchers on the rational design of catalysts.
- N-heterocycles,
- Selective hydrogenation,
- Dehydrogenation,
- Heterogeneous catalysts,
- Structure-activity relationship
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