Citation: Zhu Jihua, Zhang Hao, Liu Min, Liu Jingjiang, Liao Yuan, Quan Zhengjun, Wang Xicun. An Intramolecular Charge Transfer (ICT)-Based Fluorescent Probe of Hydrogen Sulphide under pH Control Strategy[J]. Chinese Journal of Organic Chemistry, ;2020, 40(4): 1043-1049. doi: 10.6023/cjoc201910024 shu

An Intramolecular Charge Transfer (ICT)-Based Fluorescent Probe of Hydrogen Sulphide under pH Control Strategy

Zhu Jihua ^a,b ,
Zhang Hao ^a ,
Liu Min ^a ,
Liu Jingjiang ^a ,
Liao Yuan ^a ,
Quan Zhengjun ^a,, ,
Wang Xicun ^a,,

a.
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
b.
College of Chemistry and Chemical Engineering, Longdong University, Qingyang, Gansu 745000

Corresponding author: Quan Zhengjun, quanzhengjun@hotmail.com Wang Xicun, wangxicun@nwnu.edu.cn
Received Date: 20 October 2019
Revised Date: 12 November 2019
Available Online: 11 December 2019
Fund Project: Project supported by the Longyuan Youth Innovative and Entrepreneurial Talents Project (No. 2019-39) and the Research Project of Higher Education in Gansu Province (No. 2018A-004)the Research Project of Higher Education in Gansu Province 2018A-004the Longyuan Youth Innovative and Entrepreneurial Talents Project 2019-39

Figures(10)

Hydrogen sulfide (H₂S) and pH play a most important role in vivo and environment. A fluorescent probe for fast and sensitive detection of H₂S and pH are of vital importance for research their functions. A naphthalimide-based fluorescent probe L has been designed and synthesized based on intramolecular charge transfer (ICT) mechanism by utilizing azide as recognition site. The probe L has demonstrated good stability in the pH range of 4~11. It showed satisfactory sensitivity and rapidly response (less than 3 min) to H₂S. An excellent linear relationship (R²=0.99823) displayed in the range of H₂S concentrations from 0 μmol·L^-1 to 20 μmol·L^-1 and the detection limit was 1.18 μmol·L^-1. Furthermore, in the present 30 equiv. H₂S, it was successfully applied to detection of pH with good linear relationship (R²=0.98764) in the pH range of 2~6.5. This methods provide a reference for detection of H₂S and pH value in the presence of 30 equiv. H₂S, which have potential application prospects in analytical detection and pathological analysis.
- hydrogen sulfide,
- pH,
- fluorescent probe,
- theoretical calculations,
- ICT mechanism
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