Citation: Zhu Xiang, Wu Qinglai, Li Junkai. Research Progress of Phenazine-1-carboxylic Acid and Its Analogue[J]. Chinese Journal of Organic Chemistry, ;2019, 39(10): 2744-2758. doi: 10.6023/cjoc201904023 shu

Research Progress of Phenazine-1-carboxylic Acid and Its Analogue

Zhu Xiang ^a ,
Wu Qinglai ^a,b,, ,
Li Junkai ^a,b,,

a.
School of Agriculture, Yangtze University, Jingzhou 434025
b.
Institute of Pesticides, Yangtze University, Jingzhou 434025

Corresponding author: Wu Qinglai, wql106@163.com Li Junkai, junkaili@sina.com.com
Received Date: 9 April 2019
Revised Date: 16 May 2019
Available Online: 3 October 2019
Fund Project: the National Natural Science Foundation of China 31672069the National Key R&D Program of China 2018YFD0200500Project supported by the National Key R&D Program of China (No. 2018YFD0200500), the National Natural Science Foundation of China (No. 31672069) and the Funds for Excellent Doctoral Dissertation Cultivation Program in Yangtze University

Figures(28)

Phenazine-1-carboxylic acid (PCA) as a natural product widely exists in microbial metabolites of Pseudomonads and Streptomycetes, which displays potent inhibitory activities against plant pathogens, and has medical antibacterial and antitumor effects, and so on. In this review, the biosynthesis and chemosynthesis of phenazine-1-carboxylic acid are summarized. At the same time, the diverse biological evaluations of its biosynthetic and chemosynthetic analogues are summarized, which could provide reference for the study of structural modifications and biological activities of these analogues.
- phenazine-1-carboxylic acid,
- analogues,
- research progress
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