Citation: Shen Xianfu, Peng Tianfeng, Zhou Yongyun, Xi Yongkai, Zhao Jingfeng, Yang Xiaodong, Zhang Hongbin. Progress in Total Syntheses of Dimeric Cyclotryptamine Alkaloids[J]. Chinese Journal of Organic Chemistry, ;2019, 39(10): 2685-2704. doi: 10.6023/cjoc201903058 shu

Progress in Total Syntheses of Dimeric Cyclotryptamine Alkaloids

a.
Center for Yunnan-Guizhou Plateau Chemical Functional Materials and Pollution Control, College of Biological Resource and Food Engineering, Qujing Normal University, Qujing 655011, Yunnan
b.
Key Laboratory of Natural Products Transformation and Utilization in Yunnan Province, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Kunming 650091

Corresponding author: Zhang Hongbin, zhanghb@ynu.edu.cn
Received Date: 26 March 2019
Revised Date: 18 April 2019
Available Online: 10 October 2019
Fund Project: the National Natural Science Foundation of China 2152197the Qujing Normal University 2018QN002the National Natural Science Foundation of China 21861032the Natural Science Foundation of Yunnan Province 2018FD078the Natural Science Foundation of Yunnan Province 2017FH001-020Project supported by the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT17R94), the National Natural Science Foundation of China (Nos. 2152197, 21861032), the Natural Science Foundation of Yunnan Province (Nos. 2018FD078, 2017FH001-020) and the Qujing Normal University (No. 2018QN002)the Program for Changjiang Scholars and Innovative Research Team in University IRT17R94

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As interesting synthetic targets, dimeric cyclotryptamine alkaloids bearing sterically hindered vicinal all-carbon quaternary stereocenters have attracted significant attention from the synthetic community. Stereocontrolled synthesis of the congested all-carbon quaternary stereocenters in these alkaloids presents a formidable challenge. This review summarizes the synthetic efforts towards dimeric cyclotryptamine alkaloids in the last twelve years.
- dimeric cyclotryptamine,
- alkaloids,
- vicinal quaternary carbons,
- oxindole,
- total synthesis
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