Citation: Ju Huanhuan, Sun Jiajing, Li Xiaoliu, Chen Hua. Synthesis of Aldo-quinazolinones by Iodine-Induced Oxidative Condensation of Aldoses and o-Aminobenzamides[J]. Chinese Journal of Organic Chemistry, ;2019, 39(7): 2018-2025. doi: 10.6023/cjoc201901026 shu

Synthesis of Aldo-quinazolinones by Iodine-Induced Oxidative Condensation of Aldoses and o-Aminobenzamides

Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002

Corresponding author: Li Xiaoliu, lixl@hbu.cn Chen Hua, hua-todd@163.com
Received Date: 17 January 2019
Revised Date: 4 March 2019
Available Online: 21 July 2019
Fund Project: the National Natural Science Foundation of China 21772031the National Natural Science Foundation of China 21372060Project supported by the National Natural Science Foundation of China (Nos. 21772031, 21372060)

Figures(2)

A series of aldo-quinazolinones were synthesized by a one-pot iodine-induced oxidative condensation of the unprotected mono-/di-saccharides and o-aminobenzamides in the yields of 30%~80%, providing an effective protocol for the preparation of aldo-quinazolinones. The amount of iodine has an important effect on the reaction.
- aldo-quinazolinone,
- oxidative condensation,
- iodine-induced
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