Citation: Zhu Lili, Zhang Hui, Wang Chunjie, Chen Zili. Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles[J]. Chinese Journal of Organic Chemistry, ;2018, 38(5): 1052-1064. doi: 10.6023/cjoc201710018 shu

Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles

Zhu Lili ^a,, ,
Zhang Hui ^a ,
Wang Chunjie ^a ,
Chen Zili ^b,,

a.
School of Chemistry and Chemical Engneering, Zhoukou Normal University, Zhoukou 466001
b.
Department of Chemistry, Renmin University of China, Beijing 100872

Corresponding author: Zhu Lili, lily77cq@163.com Chen Zili, zilichen@ruc.edu.cn
Received Date: 16 December 2017
Revised Date: 20 December 2017
Available Online: 10 May 2018
Fund Project: the Doctoral Scientific Research Foundation of Zhoukou Normal University ZKNUB2013001the Science and Technology Research Program of Henan Province 162300410197Project supported by the National Natural Science Foundation of China (No. 21472237), the Science and Technology Research Program of Henan Province (No. 162300410197), the Scientific Research Innovation Foundation of Zhoukou Normal University (No. ZKNUA201701) and the Doctoral Scientific Research Foundation of Zhoukou Normal University (No. ZKNUB2013001)the Scientific Research Innovation Foundation of Zhoukou Normal University ZKNUA201701the National Natural Science Foundation of China 21472237

Figures(26)

N-Substituted 1, 2, 3-triazole is an important structural unit in organic chemistry, and has widely utilized in organic synthesis, medicinal chemistry and material science. The chemistry of N¹-substituted 1, 2, 3-triazoles has attracted much attention from organic chemists, while the synthesis and application of their N²-isomers have been far less explored. The recent progress on the research field of N²-alkyl, allyl, propargyl, vinyl, aryl substituted 1, 2, 3-triazoles since year 2000 is summarized, including some research of our group. The content is classified by different synthetic methods, such as selective functionalization of 1, 2, 3-triazoles and oxidative cyclization of bisarylhydrazones or azobenzenes.
- 1, 2, 3-triazole,
- selective N²-fuctionalization,
- alkylation,
- allylation,
- propargylation,
- vinylation,
- arylation,
- cyclization
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Recent Progress in the Synthesis of N2-Substituted 1, 2, 3-Triazoles

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通讯作者: 陈斌, bchen63@163.com

Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles