Citation: Zhao Yucheng, Xiao Qiang, Wang Baoqu, Lin Jun, Yan Shengjiao. Synthesis of Iminopyrrolone Compounds[J]. Chinese Journal of Organic Chemistry, ;2017, 37(10): 2690-2696. doi: 10.6023/cjoc201705004 shu

Synthesis of Iminopyrrolone Compounds

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091

Corresponding author: Lin Jun, linjun@ynu.edu.cn Yan Shengjiao, yansj@ynu.edu.cn
Received Date: 2 May 2017
Revised Date: 16 June 2017
Available Online: 23 October 2017
Fund Project: the Talent Found in Yunnan Province 2012HB001the National Natural Science Foundation of China 21362042the National Natural Science Foundation of China 21262042the Donglu Scholar of Yunnan University and the Excellent Young Talents in Yunnan University XT412003the National Natural Science Foundation of China U1202221the National Natural Science Foundation of China 21662042the Natural Science Foundation of Yunnan Province 2017FA003Project supported by the National Natural Science Foundation of China (Nos. 21362042, 21662042, U1202221, 21262042), the Natural Science Foundation of Yunnan Province (No. 2017FA003), the Talent Found in Yunnan Province (No. 2012HB001), the Donglu Scholar of Yunnan University and the Excellent Young Talents in Yunnan University (No. XT412003)

Figures(4)

The method was constructed for synthesis of pyrrolone compounds, which was based on the reaction of 1, 1-endiamine (1) with maleic anhydride (2) in 1, 4-dioxane at reflux in alkali condition (Et₃N). As a result, a series of iminopyrrolone compounds have been synthesized by this reaction. This protocol possesses some advantages including readily available starting materials, simple operation and concise synthetic route and so on.
- iminopyrrolone,
- nitro-enamine,
- synthesis
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