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Citation: Han Enjian, Guo Yong, Chen Qingyun. Copper-Mediated Addition Reactions to Styrenes with 1, 1, 1-Trifluoro-2, 2-dichloroethane or 1, 1, 1-Trifluoro-2, 2, 2-tricholorethane[J]. Chinese Journal of Organic Chemistry, ;2017, 37(7): 1714-1720. doi: 10.6023/cjoc201702037 shu

Copper-Mediated Addition Reactions to Styrenes with 1, 1, 1-Trifluoro-2, 2-dichloroethane or 1, 1, 1-Trifluoro-2, 2, 2-tricholorethane

a.
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Corresponding author: Guo Yong, yguo@sioc.ac.cn
Received Date: 25 February 2017
Revised Date: 12 May 2017
Available Online: 23 July 2017
Fund Project: the National Natural Science Foundation of China 21421002Project supported by the National Natural Science Foundation of China (Nos. 21421002, 21672239)the National Natural Science Foundation of China 21672239

Figures(2)

An efficient CuCl/bpy-mediated atom transfer radical addition reaction of styrenes with CF₃CHCl₂ and CF₃CCl₃ is developed. Bpy which was added to enhance the reducibility of copper was crucial for activating one inert C-Cl bond of CF₃CHCl₂ and CF₃CCl₃ to form single radical adducts.
- HCFC,
- copper,
- radical,
- alkene
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