Citation: Xu Zhihong, Zhang Tao, Wang Shaokang, Li Junkai. Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy) phenyl-amino) propanoates/acetates[J]. Chinese Journal of Organic Chemistry, ;2017, 37(2): 526-532. doi: 10.6023/cjoc201608018 shu

Synthesis and Herbicidal Activities of Novel Ethyl 2-(4-(Pyridin-2-yl-oxy) phenyl-amino) propanoates/acetates

Xu Zhihong ^a ,
Zhang Tao ^b ,
Wang Shaokang ^b ,
Li Junkai ^a,*,,

a.
Hubei Collaborative Innovation Center for Grain Industry, Yangtze University, Jingzhou 434205
b.
Agricutural College, Yangtze University, Jingzhou 434205

Corresponding author: Li Junkai, junkaili@sina.com
Received Date: 23 August 2016
Revised Date: 6 September 2016

Figures(5)

Aryloxyphenoxypropionates (APPs) are a class of herbicides targeting on acetyl-coenzyme A carboxylase (ACCase) in monocot chloroplast. The article presents synthesis of twenty three novel ethyl 2-(4-(pyridin-2-yl-oxy) phenylamino)-propanoates/acetates, and their structures were characterized by ¹H NMR, HRMS and X-ray single-crystal diffraction. The herbicidal activities on barnyard grass and rape of the novel compounds were evaluated. Ethyl 2-(4-(5-nitropyridin-2-yloxy)-phenylamino) propanoate (B5) showed almost the same level of herbicidal activity on barnyard grass as commercial herbicide fluazifop-methyl which could become a potential lead compound on weeds.
- ethyl 2-(4-(pyridin-2-yl-oxy) phenylamino) propanoate/acetates,
- synthesis,
- herbicidal activity,
- acetyl-CoA carboxylase
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