Citation: Wang Jiayao, Jiang Rui, Liang Xiaomei, Jin Shuhui, Wang Daoquan, Zhang Jianjun. Efficient Synthesis of Epilactose[J]. Chinese Journal of Organic Chemistry, ;2017, 37(2): 375-384. doi: 10.6023/cjoc201608010 shu

Efficient Synthesis of Epilactose

China Agricultural University, Beijing 100193

Corresponding author: Jin Shuhui, shuhuij@cau.edu.cn Zhang Jianjun, zhangjianjun@cau.edu.cn
Received Date: 17 August 2016
Revised Date: 8 October 2016

Fund Project: National Science & Technology Pillar Program of China 2015BAK45B01

Figures(4)

Epilactose (4-O-β-D-galactopyranosyl-D-mannose) is a reducing disaccharide with satisfactory prebiotic properties. A superior synthetic methods were confirmed by screening different coupled donors and acceptors which were synthesized from D-mannose and D-galactose, respectively. This route gets 50% overall yields and all the intermediates are easily to be purified, making the route suitable for large scale preparation of the target compound. All the compounds were characterized by NMR and HRMS spectra.
- epilactose,
- D-mannose,
- D-galactose,
- synthesis
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