Citation: Ge Xin, Chen Xinzhi, Qian Chao. Progress on the Lewis-Basic Organocatalytic Asymmetric Reduction of Imines[J]. Chinese Journal of Organic Chemistry, ;2016, 36(6): 1208-1217. doi: 10.6023/cjoc201512029 shu

Progress on the Lewis-Basic Organocatalytic Asymmetric Reduction of Imines

Ge Xin ^a,b ,
Chen Xinzhi ^b ,
Qian Chao ^b,*,,

a.
School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122
b.
Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310027

Corresponding author: Qian Chao, qianchao@zju.edu.cn
Received Date: 21 December 2015
Revised Date: 26 January 2016

Fund Project: Zhejiang Provincial Public Technology Research of China Nos.2014C31123,2015C31038and the Fundamental Research Funds for the Central Universities No.JUSRP115A05Project supported by the Natural Science Foundation of China Nos.21376213,21476194

Figures(9)

Recently, the asymmetric reduction of imines catalyzed by Lewis-basic organocatalyst has been received much attention as the cheap hydrogen source and the simple post treatment. Based on the different functional groups of organocatalysts, this paper introduced formamide, pyridine amide, sulfonamide, supported and other Lewis basic organocatalysts. The structural characteristics, catalytic activity and mechanism of the Lewis-basic organocatalysts were summarized.
- imine,
- Lewis-base,
- organocatalyst,
- asymmetric reduction
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