Citation: Wei Li, Chen Xuwen, Liu Yunyun, Wan Jieping. Recent Advances in Organic Synthesis Employing Ethyl Lactate as Green Reaction Medium[J]. Chinese Journal of Organic Chemistry, ;2016, 36(5): 954-961. doi: 10.6023/cjoc201512014 shu

Recent Advances in Organic Synthesis Employing Ethyl Lactate as Green Reaction Medium

1.
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022

Corresponding author: Wan Jieping, wanjieping@jxnu.edu.cn
Received Date: 7 December 2015
Revised Date: 10 January 2016

Fund Project: Project supported by the National Natural Science Foundation of China No. 21562025and the Natural Science Foundation of Jiangxi Province No. 20151BAB203008

Figures(11)

The biomass-derivable ethyl lactate has been attracting daily increasing attention as a green medium in organic synthesis. The unique advantages of nontoxicity, low cost, complete biodegradability, high boiling point, and excellent compatibility to water and most organic compounds of this solvent cater well to the property of a green reaction medium. In recent years, ethyl lactate (EL) has been successfully used as medium in different types of organic reactions, including Suzuki-Miyaura reaction, Glaser reaction as well as cascade synthesis of heterocyclic compounds with biological activities. Based on our own research interest in this issue, the advances in organic synthesis employing EL as a green medium are summarized.
- green medium,
- ethyl lactate,
- coupling reaction,
- condensation reaction,
- cascade reaction
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