Citation: Chen Cui, Qiu Huihua. Study on the α-Acetoxylation of sp³-C-H Bonds Adjacent to Carbonyl of Arones[J]. Chinese Journal of Organic Chemistry, ;2016, 36(4): 826-829. doi: 10.6023/cjoc201510011 shu

Study on the α-Acetoxylation of sp³-C-H Bonds Adjacent to Carbonyl of Arones

Chen Cui ^, ,
Qiu Huihua

1.
College of Chemcal Engineering, Guangdong University of Petrochemical Technology, Maoming 525000

Corresponding author: Chen Cui,
Received Date: 12 October 2015
Available Online: 21 November 2015
Fund Project: 广东省优秀青年基金(No.2013LYM_0059)资助项目. (No.2013LYM_0059)

In this work, an efficient α-acetoxylation of sp³-C-H bonds adjacent to carbonyl of arones to construct α-acetoxy acetophenone derivatives was developed. The influences of reaction time, copper salts, iodine and the loading of copper salts and iodine on this transformation were investigated, and the optimal reaction conditions were also obtained. In addition, a possible reaction mechanism was proposed. This protocol with its advantages of simple procedure and high yield provides a novel valuable approach to α-acetoxy acetophenones.
- acetophenone,
- sp³-C-H bond,
- acetoxylation,
- α-acetoxy acetophenone
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沈阳化工大学材料科学与工程学院沈阳 110142

Study on the α-Acetoxylation of sp3-C-H Bonds Adjacent to Carbonyl of Arones

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通讯作者: 陈斌, bchen63@163.com

Study on the α-Acetoxylation of sp³-C-H Bonds Adjacent to Carbonyl of Arones