Citation: Nartop Dilek, Gürkan Perihan. Synthesis, Characterization and Antibacterial Activities of Unsymmetric Diimine Schiff Bases and Their Fe(Ⅲ) and Ni(Ⅱ) Complexes[J]. Chinese Journal of Inorganic Chemistry, ;2013, 29(6): 1227-1234. doi: 10.3969/j.issn.1001-4861.2013.00.227 shu

Synthesis, Characterization and Antibacterial Activities of Unsymmetric Diimine Schiff Bases and Their Fe(Ⅲ) and Ni(Ⅱ) Complexes

Nartop Dilek ¹ ,
Gürkan Perihan ²

1.
1. Department of Chemistry, Faculty of Arts and Science, Nevsehir University, Nevsehir 50300, Turkey;

Received Date: 15 February 2013
Available Online: 20 April 2013
Fund Project: Gazi Universtiy Research foundations资助项目(Supported by Gazi Universtiy Research foundations(FEF 05/2003-64) (Supported by Gazi Universtiy Research foundations(FEF 05/2003-64)(FEF 05/2005-37))。 (FEF 05/2005-37))

Three new unsymmetric diimines L, L_Me and L_Cl were synthesized by a two-step process. Initially, the starting Schiff base 2-hydroxy-N-(5-nitrofurylidene)aniline (SB-NO₂) was obtained by using 5-nitro-furfural and 2-hydroxyaniline. Nitro group of SB-NO₂ was reduced into its amino derivative, SB-NH₂, in solution. Diimines L, L_Me and L_Cl were obtained with the addition of 2-hydroxybenzaldehyde, 2-hydroxy-5-methylbenzaldehyde and 2-hydroxy-5-chlorobenzaldehyde, respectively, into SB-NH₂ solution. Dimeric, binuclear Fe(Ⅲ) and Ni(Ⅱ) complexes of these ligands were also synthesized. Diimines and their complexes were characterized by elemental analyses, LC-MS, IR, electronic spectra, ¹H and ¹³C-NMR spectra, TGA, conductivity and magnetic measurements. The antibacterial activities of the ligands and the complexes were investigated against five bacteria. All of the compounds showed moderate activities against Escherichia coli, Bacillus subtilis and Yersinia enterecolitica. The highest activity values were obtained by Fe(Ⅲ) complexes against Pseudomonas aeruginosa.
- unsymmetric Schiff bases;Fe(Ⅲ) and Ni(Ⅱ) complexes;reduction;antimicrobial activities
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