Citation:
Ziheng Zhuang, Xiao Xu, Kin Shing Chan. Superdrugs for Superbugs[J]. University Chemistry,
;2024, 39(9): 128-133.
doi:
10.3866/PKU.DXHX202309040
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The human city has faced bacterial attacks since ancient times, but on this fateful day, a superbug emerged among the bacteria, ushering in an unprecedented disaster for humanity. Fortunately, the leaders of the human city initiated the Superdrug Program, providing a ray of hope for mankind. These superbugs possess acquired drug resistance and innate drug resistance, among other extraordinary traits. How will the superdrugs tackle them one by one? Let’s bear witness to this epic battle!
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Keywords:
- Drug-resistant bacteria,
- Gram-negative bacteria,
- Antibiotics
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[1]
Laxminarayan, R.; Duse, A.; Wattal, C.; Zaidi, A. K. M.; Wertheim, H. F. L.; Sumpradit, N.; Vlieghe, E.; Hara, G. L.; Gould, I. M.; Goossens, H.; et al. Lancet Infect. Dis. 2013, 13 (12), 1057.
-
[2]
Levy, S. B.; Marshall, B. Nat. Med. 2004, 10 (Suppl. 12), S122.
-
[3]
Spratt, B. G. Proc. Royal Soc. B 1977, 196 (1124), 369.
-
[4]
Spellberg, B. Clin. Infect. Dis. 2019, 68 (6), 1076.
-
[5]
Fisher, M. A.; Plikaytis, B. B.; Shinnick, T. M. J. Bacteriol. 2002, 184 (14), 4025.
-
[6]
Kurz, S. G.; Hazra, S.; Bethel, C. R.; Romagnoli, C.; Caselli, E.; Prati, F.; Blanchard, J. S.; Bonomo, R. A. ACS Infect. Dis. 2015, 1 (6), 234.
-
[7]
Koul, A.; Dendouga, N.; Vergauwen, K.; Molenberghs, B.; Vranckx, L.; Willebrords, R.; Ristic, Z.; Lill, H.; Dorange, I.; Guillemont, J.; et al. Nat. Chem. Biol. 2007, 3 (6), 323.
-
[8]
Delcour, A. H. Biochim. Biophys. Acta Biomembr. 2009, 1794 (5), 808.
-
[9]
Kriste, A. M.; Paul, J. H. Acc. Chem. Res. 2021, 54 (6), 1322.
-
[10]
Parker, E. N.; Cain, B. N.; Hajian, B.; Ulrich, R. J.; Geddes, E. J.; Barkho, S.; Lee, H. Y.; Williams, J. D.; Raynor, M.; Caridha, D.; et al. ACS Cent. Sci. 2022, 8 (8), 1145.
-
[11]
Seefeld, M. A.; Miller, W. H.; Newlander, K. A.; Burgess, W. J.; DeWolf, W. E.; Elkins, P. A.; Head, M. S.; Jakas, D. R.; Janson, C. A.; Keller, P. M.; et al. J. Med. Chem. 2003, 46 (9), 1627.
-
[12]
Li, X. Z.; Plésiat, P.; Nikaido, H. Clin. Microbiol. Rev. 2015, 28 (2), 337.
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