Citation: Geyang Song, Dong Xue, Gang Li. Recent Advances in Transition Metal-Catalyzed Synthesis of Anilines from Aryl Halides[J]. University Chemistry, ;2024, 39(2): 321-329. doi: 10.3866/PKU.DXHX202308030 shu

Recent Advances in Transition Metal-Catalyzed Synthesis of Anilines from Aryl Halides

Geyang Song ^1,2 ,
Dong Xue ^1,2 ,
Gang Li ^1,2,,

1.
Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, Xi'an 710119, China;
2.
School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China

Corresponding author: Gang Li, gangli@snnu.edu.cn
Received Date: 7 August 2023

Aniline compounds are important organic intermediates and basic chemical raw materials, widely applied in research fields such as pharmaceuticals, agrochemicals, dyes, and functional materials. The development of efficient and versatile synthesis of aniline derivatives is one of the research hotspots that have been attracting much attention. In the past few decades, the study of transition metal-catalyzed synthesis of aniline derivatives from aryl halides has attracted significant attention from chemists due to its advantages of broad substrate applicability, good functional group compatibility, and high reaction selectivity. This review summarizes the research progress in transition metal-catalyzed synthesis of aniline derivatives from aryl halides, including: (1) palladium-catalyzed synthesis of aniline derivatives from aryl halides; (2) copper-catalyzed synthesis of aniline derivatives from aryl halides; (3) nickel-catalyzed synthesis of aniline derivatives from aryl halides.
- Transition metal-catalyzed,
- Anilines,
- Aryl halide,
- Amination reaction
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