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Citation: Zhengjie He. Enabling Phosphines: Analysis of Problem 6 of the 54th International Chemistry Olympiad[J]. University Chemistry, ;2022, 37(12): 220905. doi: 10.3866/PKU.DXHX202209050 shu

Enabling Phosphines: Analysis of Problem 6 of the 54th International Chemistry Olympiad

Zhengjie He ^,

College of Chemistry, Nankai University, Tianjin 300071, China

Corresponding author: Zhengjie He, zhengjiehe@nankai.edu.cn
Received Date: 20 September 2022

Organocatalysis has become the third kind of chemical catalysis besides enzyme and metal catalysis. Under the scientific background of nucleophilic phosphine organocatalysis, problem 6 of the 54th International Chemistry Olympiad is made up of a series of questions which are set with respects of the Lu (3+2) cycloaddition reaction including its occurrence, mechanism, asymmetric variant, and use in organic synthesis. By the diverse questionnaire, problem 6 examines contestants in respects of basic organic chemistry knowledge, learning ability, and logic analysis ability. Meanwhile, it also unveils to contestants a new function of nucleophilic phosphines as organocatalysts.
- Cycloaddition,
- Phosphine catalysis,
- Tertiary phosphine,
- Organocatalyst
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