Citation: Shuangshuang Cha, Jinpen Niu, Chuanfeng Liu, Jie Yan, Min Zhu, Wen Zhang, Mingyou Hu. 基于超分子自组装策略定性和定量检测奶粉中的三聚氰胺[J]. University Chemistry, ;2022, 37(5): 211107. doi: 10.3866/PKU.DXHX202111071 shu

基于超分子自组装策略定性和定量检测奶粉中的三聚氰胺

School of Chemistry, Xi'an Jiaotong University, Xi'an 710049, China

Corresponding author: Mingyou Hu, mingyouhu@xjtu.edu.cn
Received Date: 24 November 2021

三聚氰胺是一种应用广泛的化工原料，但在摄入人体后会形成结石，对肾功能造成极大损伤。由于其含氮量高，常被不法商家添加在奶粉中以提高奶粉含氮量，因此在食品工业中三聚氰胺的定性定量检测十分重要。本研究利用超分子自组装的策略，以三聚氰胺与氰尿酸自组装作用为基础，利用亚甲基蓝作为反应指示剂，使用操作便捷的分光光度法对奶粉中的三聚氰胺进行定性和定量检测。本方法反应条件温和、颜色变化明显、检出限低、灵敏度高，也可拆分成多个环节实验，应用于不同学时的实验教学，是一个适合本科教学环境的新颖实验。
- Melamine,
- Supramolecular self-assembly,
- Absorbance,
- Indicator
1. [1]
  Ma, M.; Bong, D. Langmuir 2011, 27, 8841.
2. [2]
  Meng, Q.; Zhang, S.; Li, C.; Yu, G.; Liu, J.; Jia, C.; Lu, J.; He, Y.; Ma, J.; Zhu, C. J. Chrom. B 2010, 878, 758.
3. [3]
  Wang, S.; Zhang, J.; Zhang, S.; Shi, F.; Feng, D.; Feng, X. Ecotox. Environ. Safe. 2021, 211, 111938.
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
  Reimschuessel, E. R.; Evans, C. B.; Stine, N.; Hasbrouck, T. D.; Mayer, C.; Nochetto, C. M. Food Chem. Toxico. 2010, 48, 2898.
10. [10]
  FDA/ORA Forensic Chemistry Center. GC-MS Screen for the Presence of Melamine.[2021-04-20]. https://www.fda.gov/cvm/GCMSMelamine.htm
11. [11]
12. [12]
13. [13]
  Takahiro, K.; Atsushi, O.; Yasuhiro, F.; Kazuhiro, N.; Shuzo, H.; Takahiro, Y.; Keiichi, T.; Kenjiro, K. Urological Research 2010, 38, 117.
14. [14]
15. [15]
16. [16]
17. [17]
  David, C. S.; Kirsti, A. T. Chem. Soc. Rev. 2001, 30, 83.
18. [18]
  Jonathan, A. Z.; John C. M.; Christopher, T. S.; Derk, A. W.; George, M. W. J. Am. Chem. Soc. 1994, 116, 2382.
1. [1]
  Jiayao Wang , Guixu Pan , Ning Wang , Shihan Wang , Yaolin Zhu , Yunfeng Li . Preparation of donor-π-acceptor type graphitic carbon nitride photocatalytic systems via molecular level regulation for high-efficient H₂O₂ production. Acta Physico-Chimica Sinica, 2025, 41(12): 100168-0. doi: 10.1016/j.actphy.2025.100168
2. [2]
  Lei Shu , Zimin Duan , Yushen Kang , Zijian Zhao , Hong Wang , Lihua Zhu , Hui Xiong , Nan Wang . An Exploration of the CO₂-Involved Carbon Cycle World. University Chemistry, 2024, 39(5): 144-153. doi: 10.3866/PKU.DXHX202309084
3. [3]
  Tiejun Su . The Construction and Application of the Calculation Formula for Endpoint Error in Precipitation Titration: A Case Study of the Mohr Method. University Chemistry, 2024, 39(11): 384-387. doi: 10.12461/PKU.DXHX202402039
4. [4]
  Ziwen Lei , Mingyin Liu , Jiayi Shi , Yahan Shan , Qi Zhang . 当超分子二肽遇上酸碱指示剂：热响应水凝胶的智能可视化. University Chemistry, 2026, 41(8): 210-219. doi: 10.12461/PKU.DXHX202508014
5. [5]
  Ying Ma , Heng Zhang . Molecular simulation study on the color-changing mechanism of phenolphthalein indicator. University Chemistry, 2026, 41(6): 335-342. doi: 10.12461/PKU.DXHX202504074
6. [6]
  Weikang Wang , Yadong Wu , Jianjun Zhang , Kai Meng , Jinhe Li , Lele Wang , Qinqin Liu . Green H₂O₂ synthesis via melamine-foam supported S-scheme Cd_0.5Zn_0.5In₂S₄/S-doped carbon nitride heterojunction: synergistic interfacial charge transfer and local photothermal effect. Acta Physico-Chimica Sinica, 2025, 41(8): 100093-0. doi: 10.1016/j.actphy.2025.100093
7. [7]
  Jing Yan , Zenan Zhang , Dongwei Ma , Xinyi Zhang , Zhuodong Ye , Xuefang Chen . Melamine-assisted topotactic transformation of MOFs into needle-like α-MoC/β-Mo₂C for high-performance electromagnetic wave absorption and corrosion resistance. Acta Physico-Chimica Sinica, 2026, 42(9): 100328-0. doi: 10.1016/j.actphy.2026.100328
8. [8]
  Xinyu CHENG , Xinran CHEN , Fei LI , Chen CHEN , NevisNathaniel L. , Kai CHEN . 两例同构的七元瓜环基超分子自组装体的合成、Hirshfeld表面分析及其性质. Chinese Journal of Inorganic Chemistry, 2026, 42(8): 1637-1646. doi: 10.11862/CJIC.20260049
9. [9]
  Yi Li , Zhaoxiang Cao , Peng Liu , Xia Wu , Dongju Zhang . Revealing the Coloration and Color Change Mechanisms of the Eriochrome Black T Indicator through Computational Chemistry and UV-Visible Absorption Spectroscopy. University Chemistry, 2025, 40(3): 132-139. doi: 10.12461/PKU.DXHX202405154
10. [10]
  Xiuhong Liu , Cunxu Yan , Yue Zhang , Xuesong Gao , Haifeng He . 一种新型荧光指示剂应用于配位滴定法中铜含量的测定——分析化学实验教学设计与实践. University Chemistry, 2026, 41(8): 389-401. doi: 10.12461/PKU.DXHX202507135
11. [11]
  Zhiran Duan , Haijing Qu , Xiangdong Xue . Construction and characterization of supramolecular assembly-based nanodrug delivery systems: a teaching practice in supramolecular chemistry experiment. University Chemistry, 2026, 41(7): 239-249. doi: 10.12461/PKU.DXHX202505021
12. [12]
  Mingyan Luo , Bixin Jin , Xiaoyu Li . 从科研到课堂：以溶液自组装科研案例为载体的高分子化学类创新实验构建. University Chemistry, 2026, 41(9): 301-312. doi: 10.12461/PKU.DXHX202509058
13. [13]
  Zhiwen HUANG , Qi LIU , Jianping LANG . W/Cu/S cluster-based supramolecular macrocycles and their third-order nonlinear optical responses. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 79-87. doi: 10.11862/CJIC.20240184
14. [14]
  Renjie Xue , Chao Ma , Jing He , Xuechao Li , Yanning Tang , Lifeng Chi , Haiming Zhang . Catassembly in the Host-Guest Recognition of 2D Metastable Self-Assembled Networks. Acta Physico-Chimica Sinica, 2024, 40(9): 2309011-0. doi: 10.3866/PKU.WHXB202309011
15. [15]
  Yujie WANG , Laobang WANG , Zheng ZHANG , Qi LIU , Jianping LANG . Construction of W/Cu/S cluster-based supramolecular compounds via alkynyl/sulfur cycloaddition and their third-order nonlinear optical properties. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 2069-2077. doi: 10.11862/CJIC.20250129
16. [16]
  Shihui Shi , Haoyu Li , Shaojie Han , Yifan Yao , Siqi Liu . Regioselectively Synthesis of Halogenated Arenes via Self-Assembly and Synergistic Catalysis Strategy. University Chemistry, 2024, 39(5): 336-344. doi: 10.3866/PKU.DXHX202312002
17. [17]
  Wenjian Zhang , Mengxin Fan , Wenwen Fei , Wei Bai . Cultivation of Critical Thinking Ability: Based on RAFT Polymerization-Induced Self-Assembly. University Chemistry, 2025, 40(4): 108-112. doi: 10.12461/PKU.DXHX202406099
18. [18]
  Yi Yang , Xin Zhou , Miaoli Gu , Bei Cheng , Zhen Wu , Jianjun Zhang . Femtosecond transient absorption spectroscopy investigation on ultrafast electron transfer in S-scheme ZnO/CdIn₂S₄ photocatalyst for H₂O₂ production and benzylamine oxidation. Acta Physico-Chimica Sinica, 2025, 41(6): 100064-0. doi: 10.1016/j.actphy.2025.100064
19. [19]
  Weifeng HUANG , Jingteng FENG , Xin WANG , Zhilong XU , Jiaxin LI , Guanghui SUN , Yan SUN , Yao SUN , Xi LIU , Yinfeng CHENG , Guangri XU , Li YANG . In-situ self-assembly of hydrated vanadium pentoxide on Zn foil for stable Zn anodes. Chinese Journal of Inorganic Chemistry, 2026, 42(3): 562-570. doi: 10.11862/CJIC.20250267
20. [20]
  Xiuyun Wang , Faqiong Zhao , Yuwen Liu , Yijun Li , Yong Fan , Dongcheng Liu , Juanjuan Song , Yanping Ren , Wan Li , Yongxian Fan , Xiuqiong Zeng , Wenwei Zhang , Mei Shi , Min Hu , Xiaohang Qiu , Weihong Li , Jinarong Zhang , Shuyong Zhang . Spectrophotometry and Suggestions on Operating Specifications for Spectrophotometer. University Chemistry, 2026, 41(3): 200-207. doi: 10.12461/PKU.DXHX202507116

Get Citation

PDF

XML

Metrics

PDF Downloads(5)
Abstract views(2095)
HTML views(249)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142