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Citation: Yaofeng Yuan, Baoxu Wang, Liangsen Huang, Jiajia Cheng. 利用核磁共振氢谱分析异构化产物[J]. University Chemistry, ;2022, 37(3): 210501. doi: 10.3866/PKU.DXHX202105010 shu

利用核磁共振氢谱分析异构化产物

School of Chemistry, Fuzhou University, Fuzhou 350108, China

Corresponding author: Yaofeng Yuan, yaofeng_yuan@fzu.edu.cn
Received Date: 28 May 2021

核磁共振是解析有机化合物结构的一种常用的方法，也是有机波谱分析课程教学中的重点内容之一。本文结合三个实例介绍了核磁共振氢谱解析思路，理论与科研实际相结合，利用核磁共振氢谱判断产物中异构体的结构，通过峰组的积分面积确定异构体的比例，以便培养学生的科学素养，激发学生的学习兴趣，提高谱图的解析能力。
- ¹H NMR spectroscopy,
- Isomers,
- Chemical shifts,
- Coupling constants,
- Structural analysis
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
  Field, L. D.; Sternhell, S.; Kalman, J. R. Organic Structures from Spectra, 4th ed.; John Wiley and Sons LTD:UK, 2007; pp. 381, 441-442.
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