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Citation: Man Zhang, Junhao Zhou, Yucheng Hua, Xiangwei Ren, Wentao Zhao, Wandong Zhang. Mechanisms Study of Ninhydrin Synthesis from Diethyl Phthalate[J]. University Chemistry, ;2020, 35(3): 82-88. doi: 10.3866/PKU.DXHX201907024 shu

Mechanisms Study of Ninhydrin Synthesis from Diethyl Phthalate

Man Zhang ^1, ,
Junhao Zhou ¹ ,
Yucheng Hua ¹ ,
Xiangwei Ren ^1,2,3 ,
Wentao Zhao ^1,2,3 ,
Wandong Zhang ^1,2,3

1.
School of Science, Tianjin University, Tianjin 300354, P. R. China;
2.
National Demonstration Center for Experimental Chemistry & Chemical Engineering Education(Tianjin University), Tianjin 300354, P. R. China;
3.
National Virtual Simulation Experimental Teaching Center for Chemistry & Chemical Engineering Education(Tianjin University);Tianjin 300354, P. R. China

Received Date: 20 July 2019

Ninhydrin was synthesized from diethyl benzene-1,2-dicarboxylate via Claisen condensation, hydrolysis, decarboxylation, nitrosation, deoximation, reduction, oxidation reaction and the possible reaction mechanisms for every unit reactions are discussed.
- 2,2-Dihydroxyindane-1,3-dione (Ninhydrin),
- Diethyl benzene-1,2-dicarboxylate,
- Mechanism
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