Citation: LI Cong, LIU Hui, HAN Yuxiang, LIU Zhibo. Nuclear Medicine: The Synergy of Radiochemistry and Molecular Medicine[J]. University Chemistry, ;2018, 33(3): 1-10. doi: 10.3866/PKU.DXHX201711038 shu

Nuclear Medicine: The Synergy of Radiochemistry and Molecular Medicine

LI Cong ^2, ,
LIU Hui ¹ ,
HAN Yuxiang ¹ ,
LIU Zhibo ^1,2

1.
College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China;
2.
Tsinghua University-Peking University Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, P. R. China

Received Date: 30 November 2017

The major progresses of nuclear medicine since 1970s are briefly reviewed. This mini-review is mainly focused on the development of[¹⁸F]2-fluoro-2-deoxy-D-glucose ([¹⁸F]FDG), which is the most widely applied PET tracer in clinic diagnosis. The investigation of[¹⁸F]FDG dated back to 1920s and was finally applied to the clinic after almost half century.[¹⁸F]FDG has been of great importance in the diagnosis of tumor, neurodegenerative diseases and cardiovascular diseases ever since. Except from[¹⁸F]FDG, the state-of-art development in peptide and protein nuclear medicines is also introduced. Along with the course of the development of nuclear medicine, several scientists who have made a great contribution to nuclear medicine are also introduced and paid at the same time with our sincere respect. With these introductions above, the authors intend to demonstrate the unique characteristic of nuclear medicine based on basic research and oriented to clinic problems. At last, the authors sincerely hope that the readers could be inspired on their own scientific researches after getting an insight into the history of classic nuclear medicines.
- Nuclear medicine,
- Positron emission tomography imaging,
- Applied chemistry
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