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Citation: ZHAO Yan-Fang, XU Lu-Bin. Experimental Design: Colorimetric Detection of Levofloxacin Based on Silver Nanoparticles[J]. University Chemistry, ;2017, 32(12): 69-73. doi: 10.3866/PKU.DXHX201706027 shu

Experimental Design: Colorimetric Detection of Levofloxacin Based on Silver Nanoparticles

ZHAO Yan-Fang ,
XU Lu-Bin

College of Chemistry and Pharmaceutical Science, Qingdao Agricultural University, Qingdao 266109, Shandong Province, P. R. China

A sensitive method based on the sodium dodecyl sulfate-stabilized silver nanoparticles (SDS-AgNPs) for detection of levofloxacin was reported. Levofloxacin could rapidly induce the aggregation of SDS-AgNPs, thereby resulting in a yellow-to-red color change. The color change could be monitored by naked eye and UV-Vis spectrophotometry. The presented method is convenient, simple, cost-effective and suitable for comprehensive laboratory teaching to develop students' innovation and scientific research ability.
- Levofloxacin,
- Silver nanoparticles,
- Sodium dodecyl sulfate (SDS),
- Instrumental analysis experiment
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