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Citation: FU Wei-Wei, YI Qing, JIN Xia, KUANG Xiang, TANG Zi-Qing. Synthesis of 4'-[5-(4-Carboxylphenylfuran)-2-yl)]-2,2':6',2"-Terpyridine: A Proposed Organic Chemistry Experiment[J]. University Chemistry, ;2017, 32(6): 82-85. doi: 10.3866/PKU.DXHX201611017 shu

Synthesis of 4'-[5-(4-Carboxylphenylfuran)-2-yl)]-2,2':6',2"-Terpyridine: A Proposed Organic Chemistry Experiment

College of Chemistry and Material Science, Hengyang Normal University, Hengyang 421008, Hunan Province, P. R. China

The synthesis and characterization of 4'-[5-(4-carboxylphenylfuran)-2-yl)]-2,2':6',2″-terpyridine is an exploratory experiment completed by senior undergraduates. 4-(5-formylfuran-2-yl) benzoic acid was obtained with furfural and 4-aminobenzoic acid as raw materials by a coupled reaction at low temperature. The target compound was obtained with 4-(5-formylfuran-2-yl) benzoic acid and 2-acetylpyridine in the presence of ammonium hydroxide and characterized by melting point, IR and ¹H NMR measurements. It is proposed as an organic chemistry experiment as it contains coupling reaction of aromatic rings, synthesis of α,β-unsaturated ketone, Michael addition reaction which would be beneficial for training of students.
- Terpyridine,
- Infrared spectrum,
- ¹H NMR spectroscopy,
- Coupling reaction,
- Michael addition
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