Home

Citation: LI Yang, FENG Hua, JIANG Denggao. Preparation and application of covalently bonded cellulose acetylsalicylate chiral stationary phases[J]. Chinese Journal of Chromatography, ;2016, 34(8): 739-744. doi: 10.3724/SP.J.1123.2016.04026 shu

Preparation and application of covalently bonded cellulose acetylsalicylate chiral stationary phases

LI Yang ^1,, ,
FENG Hua ² ,
JIANG Denggao ³

1.
1. Henan Institute for Food and Drug Control, Zhengzhou 450003, China;
2.
2. Women and Infants Hospital of Zhengzhou, Zhengzhou 450003, China;
3.
3. School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou 450001, China

Corresponding author: LI Yang,
Received Date: 15 April 2016

The chemical bonded cellulose acetylsalicylate chiral stationary phase (CSP1) was obtained by fixing cellulose derivative on silica gel with beta-(3, 4-epoxycyclohexyl) ethyl trimethoxy silane as space arm. The resolution mechanism and feasibility of CSP1 were studied by comparing CSP1 with coated chiral stationary phase prepared by cellulose acetylsalicylate. The role of cyclohexyl group in the space arm was also verified by comparing CSP1 with CSP2 which had no cyclohexyl group in the space arm. Based on the chromatographic results, the immobilized chiral stationary phase exhibited better chiral resolving abilities than coated stationary phase for imidazoles. It is due to, on the one hand, more types of mobile phases used, on the other hand, the modified cellulose by cyclohexyl group.
- cellulose acetylsalicylate,
- chiral stationary phase,
- space arm,
- bond
1. [1]
  [1] Li Y, Zhu J K, Feng H, et al. Chin J Anal Chem, 2015, 43(8): 1162
2. [2]
  [2] Okamoto Y, Kaida Y. J Chromatogr A, 1994, 666(1/2): 403
3. [3]
  [3] Zhao Y F, Song J X, Sun J Y, et al. Chinese Journal of Chromatography, 2014, 32(8): 832 赵允凤, 宋佳新, 孙嘉仪, 等. 色谱, 2014, 32(8): 832
4. [4]
  [4] Shen J, Liu S, Li P, et al. J Chromatogr A, 2012, 1246(13): 137
5. [5]
  [5] Chankvetadze B, Ikai T, Yamamoto C, et al. J Chromatogr A, 2004, 1042(S1/2): 55
6. [6]
  [6] Wang M. Chinese Journal of Chromatography, 2014, 32(2): 198 王敏. 色谱, 2014, 32(2): 198
7. [7]
  [7] Tang L, Yu H N, Li C P, et al. Chinese Journal of Pharmaceutical Analysis, 2008, 28(6): 917 唐岚, 于海宁, 李成平, 等. 药物分析杂志, 2008, 28(6): 917
1. [1]
  Qiuting Zhang , Fan Wu , Jin Liu , Zian Lin . Chromatographic Stationary Phase and Chiral Separation Using Frame Materials. University Chemistry, 2025, 40(4): 291-298. doi: 10.12461/PKU.DXHX202405174
2. [2]
  Hao YAN , Meng WANG , Chenyi HU , Ming LI , Chuanjun YUAN . Synthesis of europium complex bonded NaYF₄∶Yb, Er micron-materials and their applications in dual-mode fluorescent development of latent fingerprints. Chinese Journal of Inorganic Chemistry, 2026, 42(5): 991-1002. doi: 10.11862/CJIC.20250302
3. [3]
  Keying Qu , Jie Li , Ziqiu Lai , Kai Chen . Unveiling the Mystery of Chirality from Tartaric Acid. University Chemistry, 2024, 39(9): 369-378. doi: 10.12461/PKU.DXHX202310091
4. [4]
  Ruiying WANG , Hui WANG , Fenglan CHAI , Zhinan ZUO , Benlai WU . Three-dimensional homochiral Eu(Ⅲ) coordination polymer and its amino acid configuration recognition. Chinese Journal of Inorganic Chemistry, 2025, 41(5): 877-884. doi: 10.11862/CJIC.20250052
5. [5]
  Jingxuan Zhang , Weihao Jiang , Siyuan Zhang , Hongye Tian , Ziye Huang , Lin Huang , Qikun Wu , Jing Yang , Yibin Jiang , Cheng Wang . Automation and AI-Assisted Investigation of the Chemical Reactivity of Sulfosalicylic Acid. University Chemistry, 2026, 41(1): 332-345. doi: 10.12461/PKU.DXHX202505108
6. [6]
  Jianqiang Zheng , Yongbin Huang , Wencan Ming , Yingju Liu . Intelligent Reaction Optimization: Synthesis of Acetylsalicylic Acid Driven by Deep Learning and Optimization Algorithms. University Chemistry, 2025, 40(9): 87-98. doi: 10.12461/PKU.DXHX202411062
7. [7]
  Dongheng WANG , Si LI , Shuangquan ZANG . Construction of chiral alkynyl silver chains and modulation of chiral optical properties. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 131-140. doi: 10.11862/CJIC.20240379
8. [8]
  Jin Tong , Shuyan Yu . Crystal Engineering for Supramolecular Chirality. University Chemistry, 2024, 39(3): 86-93. doi: 10.3866/PKU.DXHX202308113
9. [9]
  Runjie Li , Hang Liu , Xisheng Wang , Wanqun Zhang , Wanqun Hu , Kaiping Yang , Qiang Zhou , Si Liu , Pingping Zhu , Wei Shao . 氨基酸的衍生及手性气相色谱分离创新实验. University Chemistry, 2025, 40(6): 286-295. doi: 10.12461/PKU.DXHX202407059
10. [10]
  Renxiao Liang , Zhe Zhong , Zhangling Jin , Lijuan Shi , Yixia Jia . A Palladium/Chiral Phosphoric Acid Relay Catalysis for the One-Pot Three-Step Synthesis of Chiral Tetrahydroquinoline. University Chemistry, 2024, 39(5): 209-217. doi: 10.3866/PKU.DXHX202311024
11. [11]
  Haiying Wang , Andrew C.-H. Sue . How to Visually Identify Homochiral Crystals. University Chemistry, 2024, 39(3): 78-85. doi: 10.3866/PKU.DXHX202309004
12. [12]
  Guilan He , Yaofeng Yuan . 手性二茂铁双膦配体Xyliphos的合成及应用. University Chemistry, 2025, 40(8): 130-137. doi: 10.12461/PKU.DXHX202409122
13. [13]
  Xilin Zhao , Xingyu Tu , Zongxuan Li , Rui Dong , Bo Jiang , Zhiwei Miao . Research Progress in Enantioselective Synthesis of Axial Chiral Compounds. University Chemistry, 2024, 39(11): 158-173. doi: 10.12461/PKU.DXHX202403106
14. [14]
  Ke QIAO , Yanlin LI , Shengli HUANG , Guoyu YANG . Advancements in asymmetric catalysis employing chiral iridium (ruthenium) complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2091-2104. doi: 10.11862/CJIC.20240265
15. [15]
  Qin Hou , Jiayi Hou , Aiju Shi , Xingliang Xu , Yuanhong Zhang , Yijing Li , Juying Hou , Yanfang Wang . Preparation of Cuprous Iodide Coordination Polymer and Fluorescent Detection of Nitrite: A Comprehensive Chemical Design Experiment. University Chemistry, 2024, 39(8): 221-229. doi: 10.3866/PKU.DXHX202312056
16. [16]
  Siming Bian , Sijie Luo , Junjie Ou . Application of van Deemter Equation in Instrumental Analysis Teaching: A New Type of Core-Shell Stationary Phase. University Chemistry, 2025, 40(3): 381-386. doi: 10.12461/PKU.DXHX202406087
17. [17]
  Jiaqi AN , Yunle LIU , Jianxuan SHANG , Yan GUO , Ce LIU , Fanlong ZENG , Anyang LI , Wenyuan WANG . Reactivity of extremely bulky silylaminogermylene chloride and bonding analysis of a cubic tetragermylene. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1511-1518. doi: 10.11862/CJIC.20240072
18. [18]
  Conghao Shi , Ranran Wang , Juli Jiang , Leyong Wang . The Illustration on Stereoisomers of Macrocycles Containing Multiple Chiral Centers via Tröger Base-based Macrocycles. University Chemistry, 2024, 39(7): 394-397. doi: 10.3866/PKU.DXHX202311034
19. [19]
  Xiaoning TANG , Junnan LIU , Xingfu YANG , Jie LEI , Qiuyang LUO , Shu XIA , An XUE . Effect of sodium alginate-sodium carboxymethylcellulose gel layer on the stability of Zn anodes. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1452-1460. doi: 10.11862/CJIC.20240191
20. [20]
  Yan'e LIU , Shengli JIA , Yifan JIANG , Qinghua ZHAO , Yi LI , Xinshu CHANG . MoO₃/cellulose derived carbon aerogel: Fabrication and performance as cathode for lithium-sulfur battery. Chinese Journal of Inorganic Chemistry, 2025, 41(8): 1565-1573. doi: 10.11862/CJIC.20250054

Get Citation

PDF

XML

Metrics

PDF Downloads(4)
Abstract views(757)
HTML views(84)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return