引用本文:
宋斌, 郑长征, 张铭凯, 徐守卫, 任立娣. 2-呋喃甲酰腙衍生物的合成、荧光性质及抑菌活性[J]. 应用化学,
2014, 31(7): 793-798.
doi:
10.3724/SP.J.1095.2014.30454
Citation: SONG Bin, ZHENG Changzheng, ZHANG Mingkai, XU Shouwei, REN Lidi. Synthesis,Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives[J]. Chinese Journal of Applied Chemistry, 2014, 31(7): 793-798. doi: 10.3724/SP.J.1095.2014.30454
Citation: SONG Bin, ZHENG Changzheng, ZHANG Mingkai, XU Shouwei, REN Lidi. Synthesis,Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives[J]. Chinese Journal of Applied Chemistry, 2014, 31(7): 793-798. doi: 10.3724/SP.J.1095.2014.30454
2-呋喃甲酰腙衍生物的合成、荧光性质及抑菌活性
English
Synthesis,Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives
Abstract:
Four furan acylhydrazones derivatives(4a~4d) were synthesized from 2-furancarbaldehyde and benzohydrazide derivatives and characterized by using elemental analysis,1H NMR,FT-IR,UV and fluorescence spectroscopy methods.The results show that the 2D chain layered structure was assembled through intermolecular hydrogen bonds and face to face π…π stacking interactions of the furan rings.The single crystal of acylhydrazone 4a was obtained through the solvent evaporation method.Its crystal and molecular structures were determined through X-ray scattering.Fluorescence test shows that the acylhydrazone 4c has strong fluorescence.All furan acylhydrazones were screened for their antibacterial activities to Escherichia coli,Staphylococcus aureus and Pseudomonas aeruginosa by agar diffusion method.The result shows that acylhydrazone 4c has very significant antibacterial activity to Staphylococcus aureus.
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Key words:
- furan acylhydrazone
- / crystal structure
- / luminescence property
- / antibacterial activity
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