引用本文:
刘宏, 薛金萍, 江舟, 陈耐生, 黄金陵. 肿瘤光动力治疗临床应用的光敏剂及其研究概况[J]. 应用化学,
2013, 30(12): 1386-1392.
doi:
10.3724/SP.J.1095.2013.30375
Citation: LIU Hong, XUE Jinping, JIANG Zhou, CHEN Naisheng, HUANG Jinling. Photosensitizer Used in Clinical Photodynamic Thearpy for Cancer[J]. Chinese Journal of Applied Chemistry, 2013, 30(12): 1386-1392. doi: 10.3724/SP.J.1095.2013.30375
Citation: LIU Hong, XUE Jinping, JIANG Zhou, CHEN Naisheng, HUANG Jinling. Photosensitizer Used in Clinical Photodynamic Thearpy for Cancer[J]. Chinese Journal of Applied Chemistry, 2013, 30(12): 1386-1392. doi: 10.3724/SP.J.1095.2013.30375
肿瘤光动力治疗临床应用的光敏剂及其研究概况
English
Photosensitizer Used in Clinical Photodynamic Thearpy for Cancer
Abstract:
Photodynamic therapy (PDT) has emerged as a selective and non-invasive modality for the treatment of malignant tumors. Photosensitizers are the key component of PDT,which generates cytotoxic reactive oxygen species (ROS) in the presence of oxygen and light with appropriate wavelength. In clinical practice,three families of photosensitizer (PS) are used,including porphyrins,chlorophylls and bacteriochloyin/phthalocyanines. This review focused on the oncologic photosensilizers that were in clinical uses or trials and from the points of view of successful photosensitizers explored the future trends of PS and PDT.
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