引用本文:
李龙珠, 黄紫洋, 林妍, 曹媚, 林剑群. 羟基磷灰石/氧化铁复合涂层的制备及其诱导骨生长的生物活性[J]. 应用化学,
2013, 30(10): 1149-1155.
doi:
10.3724/SP.J.1095.2013.20559
Citation: LI Longzhu, HUANG Ziyang, LIN Yan, CAO Mei, LIN Jianqun. Preparation and Bioactivity for Inducing Bone Growth of Hydroxyapatite/Fe2O3 Composite Coating[J]. Chinese Journal of Applied Chemistry, 2013, 30(10): 1149-1155. doi: 10.3724/SP.J.1095.2013.20559
Citation: LI Longzhu, HUANG Ziyang, LIN Yan, CAO Mei, LIN Jianqun. Preparation and Bioactivity for Inducing Bone Growth of Hydroxyapatite/Fe2O3 Composite Coating[J]. Chinese Journal of Applied Chemistry, 2013, 30(10): 1149-1155. doi: 10.3724/SP.J.1095.2013.20559
羟基磷灰石/氧化铁复合涂层的制备及其诱导骨生长的生物活性
摘要:
用电泳沉积法制得羟基磷灰石/壳聚糖/氧化铁(HA/CS/Fe2O3)复合涂层,经700℃烧结处理得到HA/Fe2O3复合涂层。通过SEM、EDS、XRD、FT-IR、电化学和万能材料试验机等对复合涂层的表面形貌、物相组成、抗腐蚀性和结合强度进行了表征和测试,最后采用1.5SBF浸泡法对复合涂层的生物活性进行了评价。结果表明,当悬浮液中的HA、CS与Fe2O3质量比为100:100:1时,所制得的HA/Fe2O3复合涂层表面粗糙,抗腐蚀性强,具有良好的诱导骨生长生物活性,基体与复合涂层结合强度可达27.5 MPa。
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关键词:
- 羟基磷灰石/氧化铁复合涂层
- / 电泳沉积
- / 生物活性
English
Preparation and Bioactivity for Inducing Bone Growth of Hydroxyapatite/Fe2O3 Composite Coating
Abstract:
Electrophoretic deposition (EPD) has been exploited for the preparation of hydroxyapatite/chitosan/ferric oxide (HA/CS/Fe2O3) composite coating,which was then sintered at 700℃ for 2 h to yield HA/Fe2O3 composite coating. The surface morphology,phase composition,corrosion resistance and adhesion between the composite coating and substrate were characterized by SEM,EDS and XRD,FT-IR,electrochemical instrument and Lloyd LR5K Plus Testing Instrument,respectively. The bioactivity for inducing bone growth of the HA/Fe2O3 composite coating was evaluated in 1.5 times of ionic concentration of simulated body fluid (1.5SBF). When the mass ratio of HA:CS:Fe2O3 in the suspension was 100:100:1,the resultant HA/Fe2O3 composite coating had rough surface and strong adhesion up to 27.5 MPa with substrate and showed high corrosion resistance in 1.5SBF and excellent bioactivity for inducing bone growth in 1.5SBF.
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