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Citation: FAN Jun, QIU Xin, TIAN Zheng, ZHANG Deping, SUN Wei, LI Yangde, LI Weirong, MENG Jian. Microstructure and in vitro Degradation Resistance of Mg-Y-Zn-Zr Alloys as Biomaterials[J]. Chinese Journal of Applied Chemistry, ;2012, 29(12): 1452-1456. doi: 10.3724/SP.J.1095.2012.20436 shu

Microstructure and in vitro Degradation Resistance of Mg-Y-Zn-Zr Alloys as Biomaterials

FAN Jun ^a,c ,
QIU Xin ^a ,
TIAN Zheng ^a ,
ZHANG Deping ^a ,
SUN Wei ^a ,
LI Yangde ^b ,
LI Weirong ^b ,
MENG Jian ^a,,

1.
a Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;
2.
b Dongguan Yian Science & Technology Co. Ltd, Dongguan 523000, China;
3.
c University of Chinese Academy of Sciences, Beijing 100049, China

Corresponding author: MENG Jian,
Received Date: 28 September 2012
Available Online: 22 October 2012
Fund Project: 国家科技支撑计划(2012BAE01B04,2011BAE22B01) (2012BAE01B04,2011BAE22B01)

Mg-1.5Y-1.2Zn-0.44Zr alloys by adding small amounts(mass fraction) of yttrium(1.5%),zinc(1.2%) and zirconium(0.35%) into pure magnesium were developed as degradable metallic biomaterials.Also,solution treatment and hot extrusion were used as the methods for fabrication.An investigation of microstructure and in vitro degradation responses were made.The alloys are mainly composed of the matrix α-Mg phases and the Mg₁₂ZnY secondary phases.The grains of the as-cast alloys were significantly refined by hot extrusion.The biodegradation resistance of the as-cast alloys is obviously improved by hot extrusion via microstructure refinement.The results of in vitro degradation responses in the simulated body fluid(SBF) indicate that the product of degradation precipitated on the alloy's surface is the phosphate which contains Ca and Mg elements.
- biomaterials,
- Mg-Y-Zn-Zr,
- microstructure,
- in vitro degradation
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