基于聚中性红/多壁碳纳米管复合材料的比率型电化学传感器检测雌三醇

引用本文: 孙志远, 樊文芳, 王勇, 庄欠粉. 基于聚中性红/多壁碳纳米管复合材料的比率型电化学传感器检测雌三醇[J]. 分析化学, 2023, 51(1): 42-52. doi: 10.19756/j.issn.0253-3820.221543 shu

Citation: SUN Zhi-Yuan, FAN Wen-Fang, WANG Yong, ZHUANG Qian-Fen. Poly(neutral red)/Multi-walled Carbon Nanotube Composite Modified Electrochemical Sensor for Ratiometric Detection of Estriol[J]. Chinese Journal of Analytical Chemistry, 2023, 51(1): 42-52. doi: 10.19756/j.issn.0253-3820.221543 shu

基于聚中性红/多壁碳纳米管复合材料的比率型电化学传感器检测雌三醇

南昌大学化学化工学院, 南昌 330031

通讯作者: 庄欠粉,E-mail:qfzhuang@ncu.edu.cn

基金项目:
国家自然科学基金项目(Nos.31960495,32160600,21864017)资助。

摘要: 基于聚中性红/多壁碳纳米管复合材料构建了检测雌三醇的比率型电化学传感器,利用聚中性红作为内参比电活性探针,雌三醇与聚中性红的氧化峰电流比值作为比率电化学信号,实现了雌三醇的定量检测。聚中性红/多壁碳纳米管复合材料具有良好的电导率和电催化性能,可提高检测灵敏度。实验结果表明,雌三醇在聚中性红/多壁碳纳米管复合材料修饰的玻碳电极上发生双电子和双质子的电化学氧化过程。传感器检测雌三醇的线性范围为0.1~2.0μmol/L,检出限为0.08μmol/L(S/N=3)。此传感器具有灵敏度高、抗干扰能力强及稳定性好等优点,可用于雌三醇药膏、人尿液和湖水样中雌三醇的分析。

关键词:

English

Poly(neutral red)/Multi-walled Carbon Nanotube Composite Modified Electrochemical Sensor for Ratiometric Detection of Estriol

School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China

Corresponding author: ZHUANG Qian-Fen, qfzhuang@ncu.edu.cn

Received Date: 03 November 2022
Revised Date: 23 November 2022
Fund Project:
Supported by the National Natural Science Foundation of China (Nos.31960495, 32160600, 21864017).

Abstract: A poly(neutral red)/multi-walled carbon nanotube nanocomposite modified electrochemical sensor was established for ratiometric sensing of estriol. The poly(neutral red) was used as the internal reference electroactive probe, and the oxidation peak current ratio of estriol to poly(neutral red) was used for accurate quantitative detection of estriol. The poly(neutral red)/multi-walled carbon nanotube nanocomposite was demonstrated good electroconductivity and high electrocatalytic performance which could improve the detection sensitivity. The response of the ratiometric sensor was linearly proportion to the estriol concentration in the 0.1-2.0 μmol/L range, with a limit of detection (S/N=3) of 0.08 μmol/L. The electrochemical oxidation reaction of estriol on the poly(neutral red)/multiwalled carbon nanotube nanocomposite/glassy carbon electrode was demonstrated to undergo a two-electron/two-proton process. Moreover, the sensor had high sensitivity, strong anti-interference ability and good stability, and was successfully applied to testriol analysis in pharmaceutical cream, urine and lake water samples.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

基于聚中性红/多壁碳纳米管复合材料的比率型电化学传感器检测雌三醇

通讯作者: 庄欠粉,E-mail:qfzhuang@ncu.edu.cn

English

Poly(neutral red)/Multi-walled Carbon Nanotube Composite Modified Electrochemical Sensor for Ratiometric Detection of Estriol

Corresponding author: ZHUANG Qian-Fen, qfzhuang@ncu.edu.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

基于聚中性红/多壁碳纳米管复合材料的比率型电化学传感器检测雌三醇

通讯作者: 庄欠粉,E-mail:qfzhuang@ncu.edu.cn

English

Poly(neutral red)/Multi-walled Carbon Nanotube Composite Modified Electrochemical Sensor for Ratiometric Detection of Estriol

Corresponding author: ZHUANG Qian-Fen, qfzhuang@ncu.edu.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs