Citation: QI Yu, LU Yang, ZHOU Qing-Qing, KAN Zi-Tong, YANG Long, BAI Xue, DONG Biao, XU Lin. Application of High Performance Hydrogels in Wearable Sensors[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(11): 1699-1711. doi: 10.19756/j.issn.0253-3820.221352 shu

Application of High Performance Hydrogels in Wearable Sensors

QI Yu ¹ ,
LU Yang ² ,
ZHOU Qing-Qing ¹ ,
KAN Zi-Tong ¹ ,
YANG Long ¹ ,
BAI Xue ¹ ,
DONG Biao ¹ ,
XU Lin ^1,,

1.
State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China;
2.
Department of Cardiovascular, the Second Hospital of Jilin University, Changchun 130041, China

Corresponding author: XU Lin, linxu@jlu.edu.cn
Received Date: 15 July 2022
Revised Date: 15 September 2022

Fund Project: Supported by the National Natural Science Foundation of China (Nos.61874049, 61822506, 11874181), the Natural Science Foundation of Jilin Province, China (Nos.20200801017GH, 20190303012SF) and the Fundamental Research Funds for the Central Universities of China.

With the continuous advancement of information technology, sensors are developing in the direction of flexibility, wearability and intelligence. Wearable sensors with the advantages including light weight, low modulus, low cost, high elasticity and stretch ability can meet the needs of intelligent development of the Internet of Things, and thus have received extensive attention. As a new type of flexible material, hydrogel has many advantages such as excellent mechanical properties, high flexibility, good fit with human skin and high biocompatibility, and it is expected to become a platform for a new generation of wearable sensors. However, due to the issues in stability of hydrogels, tolerance to extreme environments such as drought and cold, limitations in electrical conductivity, mechanical properties, and low integration, their applications and development in the field of wearable sensors are limited. This paper focuses on the improvement of the above issues and the applications of conductive hydrogels in wearable sensors in different fields such as strain sensing, tactile sensing, gas sensing, humidity sensing, temperature sensing, etc., and finally summarizes the existing problems of hydrogels.
- Hydrogels,
- Sensor,
- Wearable devices,
- Review
1. [1]
  CONG J, ZHANG X M, CHEN K S, XU J. Sens. Actuators, B, 2002, 87(3):487-490.
2. [2]
  THAM J C K. J. Tech. Writing Commun., 2017, 47(1):22-55.
3. [3]
  ALRAMMOUZ R, PODLECKI J, ABBOUD P, SORLI B, HABCHI R. Sens. Actuators, A, 2018, 284:209-231.
4. [4]
  BORGERSON S G. Foreign Affairs, 2008, 87(2):63-77.
5. [5]
  CHENG B C, WU P Y. ACS Nano, 2021, 15(5):8676-8685.
6. [6]
  DOHERTY S T, LEMIEUX C J, CANALLY C. Soc. Sci. Med., 2014, 106:83-92.
7. [7]
  TRUNG T Q, DUY L T, RAMASUNDARAM S, LEE N E. Nano Res., 2017, 10(6):2021-2033.
8. [8]
  LARA O D, LABRADOR M A. IEEE Commun. Surv. Tut., 2012, 15(3):1192-1209.
9. [9]
  LIANG Y N, WU Z X, WEI Y M, DING Q L, ZILBERMAN M, TAO K, XIE X, WU J. Nano-micro Lett., 2022, 14(1):1-19.
10. [10]
  World Health Organization. World Health Statistics 2016:Monitoring Health for the SDGs Sustainable Development Goals[M]. World Health Organization, 2016.
11. [11]
  GAO W, EMAMINEJAD S, NYEIN H Y Y, CHALLA S, CHEN K, PECK A, FAHAD H M, OTA H, SHIRAKI H, KIRIYA D. Nature, 2016, 529(7587):509-514.
12. [12]
  HAICK H, TANG N. ACS Nano, 2021, 15(3):3557-3567.
13. [13]
  PRUVSS-UVSTUVN A, CORVALÁN C F. World Health Organization. Preventing Disease Through Healthy Environments:Towards an Estimate of the Environmental Burden of Disease:Executive Summary. 2006.
14. [14]
  RODGERS M M, PAI V M, CONROY R S. IEEE Sen. J., 2014, 15(6):3119-3126.
15. [15]
  DIEFFENDERFER J, GOODELL H, MILLS S, MCKNIGHT M, YAO S S, LIN F Y, BEPPLER E, BENT B, LEE B, MISRA V. IEEE J. Biomed. Health, 2016, 20(5):1251-1264.
16. [16]
  HUANG S M, XU S Y, BELOPOLSKI I, LEE C C, CHANG G Q, WANG B K, ALIDOUST N, BIAN G, NEUPANE M, ZHANG C L, JIA S, BANSIL A, LIN H, HASAN M Z. Nat. Commun., 2015, 6:7373.
17. [17]
  KIM J, CAMPBELL A S, WANG J. Talanta, 2018, 177:163-170.
18. [18]
  BAI J H, WANG R, JU M X, ZHOU J X, ZHANG L X, JIAO T F. Sci. China Mater., 2021, 64(4):942-952.
19. [19]
  ZHANG Y, LIANG B, JIANG Q F, LI Y, FENG Y, ZHANG L Q, ZHAO Y M, XIONG X L. Smart Mater. Struct., 2020, 29(7):075027.
20. [20]
  LEE K Y, MOONEY D J. Chem. Rev., 2001, 101(7):1869-1880.
21. [21]
  EL-HAFIAN E A, ELGANNOUDI E S, MAINAL A, YAHAYA A H B. Turk. J. Chem., 2010, 34(1):47-56.
22. [22]
  CHEN Z, CHEN Y J, HEDENQVIST M S, CHEN C, CAI C, LI H, LIU H Z, FU J. J. Mater. Chem. B, 2021, 9(11):2561-2583.
23. [23]
  CUI C, FU Q J, MENG L, HAO S W, DAI R G, YANG J. ACS Appl. Bio Mater., 2020, 4(1):85-121.
24. [24]
  LI S N, ZHOU X, DONG Y M, LI J H. Macromol. Rapid Commun., 2020, 41(23):2000444.
25. [25]
  ZHOU H W, LAI J L, ZHENG B H, JIN X L, ZHAO G X, LIU H B, CHEN W X, MA A, LI X S, WU Y P. Adv. Funct. Mater., 2022, 32(1):2108423.
26. [26]
  CAI P Q, CHEN X D. ACS Mater. Lett., 2019, 1(2):285-289.
27. [27]
  JAMAL M, AHMAD W, ANDLEEB S, JALIL F, IMRAN M, NAWAZ M A, HUSSAIN T, ALI M, RAFIQ M, KAMIL M A. J. Chin. Med. Assoc., 2018, 81(1):7-11.
28. [28]
  RICHTER A, BUND A, KELLER M, ARNDT K F. Sens. Actuators, B, 2004, 99(2-3):579-585.
29. [29]
  CENSI R, DI M P, VERMONDEN T, HENNINK W. J. Controlled Release, 2012, 161(2):680-692.
30. [30]
  ZHAO S F, LI J H, CAO D X, ZHANG G P, LI J, LI K, YANG Y, WANG W, JIN Y F, SUN R. ACS Appl. Mater. Interfaces, 2017, 9(14):12147-12164.
31. [31]
  SUN D, FENG Y F, SUN S C, YU J, JIA S Y, DANG C, HAO X, YANG J, REN W F, SUN R C, SHAO C Y, PENG F. Adv. Funct. Mater., 2022, 32(28):2201335.
32. [32]
  WU J, WU Z X, XU H H, WU Q, LIU C, YANG B R, GUI X C, XIE X, TAO K, SHEN Y. Mater. Horiz., 2019, 6(3):595-603.
33. [33]
  CHO B, YOON J, HAHM M G, KIM D H, KIM A R, KAHNG Y H, PARK S W, LEE Y J, PARK S G, KWON J D. J. Mater. Chem. C, 2014, 2(27):5280-5285.
34. [34]
  WU Z X, YANG X, WU J. ACS Appl. Mater. Interfaces, 2021, 13(2):2128-2144.
35. [35]
  ZHANG X F, MA X F, HOU T, GUO K C, YIN J Y, WANG Z G, SHU L, HE M, YAO J F. Angew. Chem., Int. Ed., 2019, 58(22):7366-7370.
36. [36]
  CUI C, SHAO C Y, MENG L, YANG J. ACS Appl. Mater. Interfaces, 2019, 11(42):39228-39237.
37. [37]
  JI D, PARK J M, OH M S, NGUYEN T L, SHIN H, KIM J S, KIM D, PARK H S, KIM J. Nat. Commun., 2022, 13(1):3019.
38. [38]
  MORELLE X P, ILLEPERUMA W R, TIAN K, BAI R B, SUO Z G, VLASSAK J J. Adv. Mater., 2018, 30(35):1801541.
39. [39]
  LIANG Y Z, LIANG H Y. Adv. Mater. Technol., 2021, 6(7):2001234.
40. [40]
  YE Y H, ZHANG Y F, CHEN Y, HAN X S, JIANG F. Adv. Funct. Mater., 2020, 30(35):2003430.
41. [41]
  FENG E, LI X, LI J J, YAN Z, ZHENG G C, GAO W, LI Z L, MA X X, YANG Z M. J. Mater. Chem. C, 2021, 9(43):15530-15541.
42. [42]
  CAI C C, WEN C Y, ZHAO W Q, TIAN S, LONG Y, ZHANG X Y, SUI X J, ZHANG L, YANG J. ACS Appl. Mater. Interfaces, 2022, 14(20):23692-23700.
43. [43]
  YUK H, ZHANG T, PARADA G A, LIU X Y, ZHAO X H. Nat. Commun., 2016, 7:12028.
44. [44]
  NIU R, QIN Z H, JI F, XU M, TIAN X L, LI J J, YAO F L. Soft Matter, 2017, 13(48):9237-9245.
45. [45]
  LIN P, MA S H, WANG X L, ZHOU F. Adv. Mater., 2015, 27(12):2054-2059.
46. [46]
  SUN J Y, ZHAO X, ILLEPERUMA W R K. Nature, 2012, 489(7414):133-136.
47. [47]
  LIU M X, LI W D, RONG J H, ZHOU C R. Colloid Polym. Sci., 2012, 290(10):895-905.
48. [48]
  LIU M X, HUANG J D, LUO B H, ZHOU C R. Int. J. Biol. Macromol., 2015, 78:23-31.
49. [49]
  GONG J P, KATSUYAMA Y, KUROKAWA T. Adv. Mater., 2003, 15(14):1155-1158.
50. [50]
  GONG J P. Soft Matter, 2010, 6(12):2583-2590.
51. [51]
  SI Y, WANG L H, WANG X Q, TANG N, YU J Y, DING B. Adv. Mater., 2017, 29(24):1700339.
52. [52]
  KONWAR A, KALITA S, KOTOKY J, CHOWDHURY D. ACS Appl. Mater. Interfaces, 2016, 8(32):20625-20634.
53. [53]
  LIU S J, LI L. ACS Appl. Mater. Interfaces, 2016, 8(43):29749-29758.
54. [54]
  CHEN Q, ZHU L, ZHAO C, WANG Q M, ZHENG J. Adv. Mater., 2013, 25(30):4171-4176.
55. [55]
  CHEN Q, ZHU L, HUANG L, CHEN H, XU K, TAN Y, WANG P X, ZHENG J. Macromolecules, 2014, 47(6):2140-2148.
56. [56]
  JIANG H C, DUAN L J, REN X Y, GAO G H. Eur. Polym. J., 2019, 112:660-669.
57. [57]
  HAN L, WANG M H, PRIETO-LÓPEZ L O, DENG X, CUI J X. Adv. Funct. Mater., 2020, 30(7):1907064.
58. [58]
  NELE V, WOJCIECHOWSKI J P, ARMSTRONG J P, STEVENS M M. Adv. Funct. Mater., 2020, 30(42):2002759.
59. [59]
  WANG C, LIU Y, QU X C, SHI B J, ZHENG Q, LIN X B, CHAO S Y, WANG C Y, ZHOU J, SUN Y. Adv. Mater., 2022, 34(16):2105416.
60. [60]
  ZHANG X N, WANG Y J, SUN S T, HOU L, WU P Y, WU Z L, ZHENG Q. Macromolecules, 2018, 51(20):8136-8146.
61. [61]
  JING H C, HE L, FENG J Y, FU H, GUAN S, GUO P P. Soft Matter, 2019, 15(26):5264-5270.
62. [62]
  HUANG Y W, XIAO L Y, ZHOU J, LIU T, YAN Y Q, LONG S J, LI X F. Adv. Funct. Mater., 2021, 31(37):2103917.
63. [63]
  WU J, WU Z X, LU X, HAN S J, YANG B R, GUI X C, TAO K, MIAO J M, LIU C. ACS Appl. Mater. Interfaces, 2019, 11(9):9405-9414.
64. [64]
  LIAO H, GUO X L, WAN P B, YU G H. Adv. Funct. Mater., 2019, 29(39):1904507.
65. [65]
  WU M, WANG X, XIA Y F, ZHU Y, ZHU S L, JIA C Y, GUO W Y, LI Q Q, YAN Z G. Nano Energy, 2022, 95:106967.
66. [66]
  FENG E, LI J J, ZHENG G C, YAN Z, LI X, GAO W, MA X X, YANG Z M. ACS Sustainable Chem. Eng., 2021, 9(21):7267-7276.
67. [67]
  SUN H L, ZHAO Y, JIAO S L, WANG C F, JIA Y P, DAI K, ZHENG G Q, LIU C T, WAN P B, SHEN C Y. Adv. Funct. Mater., 2021, 31(24):2101696.
68. [68]
  CHEN S, SUN L J, ZHOU X J, GUO Y F, SONG J C, QIAN S H, LIU Z H, GUAN Q B, MEADE J E, LIU W G, WANG Y D, HE C L, YOU Z W. Nat. Commun., 2020, 11(1):1107.
69. [69]
  LI S Y, LIU G Q, WEN H, LIU G Y, WANG H, YE M D, YANG Y, GUO W X, LIU Y F. Adv. Funct. Mater., 2022, 32(19):2111747.
70. [70]
  CHORTOS A, LIU J, BAO Z N. Nat. Mater., 2016, 15(9):937-950.
71. [71]
  ABRAIRA V E, GINTY D D. Neuron, 2013, 79(4):618-639.
72. [72]
  LI Z K, ZHANG S M, CHEN Y H, LING H N, ZHAO L B, LUO G X, WANG X C, HARTEL M C, LIU H, XUE Y M. Adv. Funct. Mater., 2020, 30(49):2003601.
73. [73]
  LIU Y M, WONG T H, HUANG X C, YIU C K, GAO Y Y, ZHAO L, ZHOU J K, PARK W, ZHAO Z, YAO K M. Nano Energy, 2022, 99:107442.
74. [74]
  WU J, WU Z X, WEI Y M, DING H J, HUANG W X, GUI X C, SHI W X, SHEN Y, TAO K, XIE X. ACS Appl. Mater. Interfaces, 2020, 12(16):19069-19079.
75. [75]
  WU J, WU Z X, HUANG W X, YANG X, LIANG Y N, TAO K, YANG B R, SHI W X, XIE X. ACS Appl. Mater. Interfaces, 2020, 12(46):52070-52081.
76. [76]
  WU Z X, RONG L M, YANG J L, WEI Y M, TAO K, ZHOU Y B, YANG B R, XIE X, WU J. Small, 2021, 17(52):2104997.
77. [77]
  WEI Y M, WANG H, DING Q L, WU Z X, ZHANG H, TAO K, XIE X, WU J. Mater. Horiz., 2022, 9(7):1921-1934.
78. [78]
  GAO Y, JIA F, GAO G H. Chem. Eng. J., 2022, 430:132919.
79. [79]
  LI T, LI L H, SUN H W, XU Y, WANG X W, LUO H, LIU Z, ZHANG T. Adv. Sci., 2017, 4(5):1600404.
80. [80]
  WEI Y, QIAN Y Y, ZHU P H, XIANG L J, LEI C F, QIU G, WANG C Y, LIU Y K, LIU Y J, CHEN G. Cellulose, 2022, 29(7):3829-3844.
81. [81]
  GU J F, HUANG J R, CHEN G Q, HOU L X, ZHANG J, ZHANG X, YANG X X, GUAN L H, JIANG X C, LIU H Y. ACS Appl. Mater. Interfaces, 2020, 12(36):40815-40827.
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