羟基螺吡喃探针可视化检测果酸类化妆品的pH值

扈洪志 周自强 夏凌 李攻科 肖小华

引用本文: 扈洪志, 周自强, 夏凌, 李攻科, 肖小华. 羟基螺吡喃探针可视化检测果酸类化妆品的pH值[J]. 分析化学, 2023, 51(1): 34-41. doi: 10.19756/j.issn.0253-3820.221198 shu
Citation:  HU Hong-Zhi,  ZHOU Zi-Qiang,  XIA Ling,  LI Gong-Ke,  XIAO Xiao-Hua. Visual Detection of pH Value of Fruit Acid Cosmetics Based on Hydroxyl Spiropyran Probe[J]. Chinese Journal of Analytical Chemistry, 2023, 51(1): 34-41. doi: 10.19756/j.issn.0253-3820.221198 shu

羟基螺吡喃探针可视化检测果酸类化妆品的pH值

    通讯作者: 李攻科,E-mail:cesgkl@mail.sysu.edu.cn; 肖小华,E-mail:xiaoxhua@mail.sysu.edu.cn
  • 基金项目:

    国家自然科学基金面上项目(Nos.21976213,21874159,22076223)和国家自然科学基金重点项目(No.22134007)资助。

摘要: 基于螺吡喃酸致变色性质制备了一种用于可视化检测果酸类化妆品pH值的探针。通常,螺吡喃分子的水溶性较差,未经修饰的螺吡喃难以应用于含水体系的测定。本研究通过在螺吡喃上修饰羟基基团调控探针的pKa值从而改善其水溶性,拓宽其使用范围,并基于此制备了对H+具有识别能力的探针。采用核磁共振氢谱(1H NMR)、核磁共振碳谱(13C NMR)、红外光谱(IR spectra)和高分辨质谱(HRMS)对研制的多羟基螺吡喃(SP-OH)探针进行了表征,考察了探针浓度、含水量及其它阳离子对吸光度的影响。紫外-可见(UV-Vis)吸收光谱显示,H+浓度(pH值)与探针在420和560nm处的吸光度的比值呈线性关系,标准曲线方程为A420nm/A560nm=-55.66pH+276.83(R2=0.996),线性范围为pH3.0~5.0。通过1H NMR、分子轨道能级计算验证了探针在酸性溶液下自发地快速转化为有色的开环体。采用SP-OH探针对果酸类化妆品的pH值进行测定,在pH3.0~5.0范围内,本方法可在5min内完成对样品pH值的测定,测定结果与商品化pH计测得结果一致,相对误差为2.4%。

English


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  • 收稿日期:  2022-04-23
  • 修回日期:  2022-08-20
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