Citation: QIN Ying-Kai, LI Shuang, HONG Yang, WANG Zhi-Guang, JI Guang-Na, CHEN Rui-Peng, ZHAO Xu-Dong, WANG Yu, REN Shu-Yue, HAN Dian-Peng, PENG Yuan, ZHOU Huan-Ying, GAO Zhi-Xian, HAN Tie. Research Process of Synthesis, Functionalization and Application of Upconversion Nanoparticles in Food Safety Detection[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(12): 1955-1969. doi: 10.19756/j.issn.0253-3820.210487 shu

Research Process of Synthesis, Functionalization and Application of Upconversion Nanoparticles in Food Safety Detection

Institute of Environmental and Operational Medicine, Academy of Military Medical Science, Academy of Military Science, Tianjin 300050, China

Corresponding author: GAO Zhi-Xian, HAN Tie,
Received Date: 8 May 2021
Revised Date: 9 September 2021

Fund Project: Supported by the National Key Research and Development Program of China(No.2018YFC1603500).

Upconversion nanoparticles (UCNPs) can convert low-energy excitation into high-energy emission via multiphoton absorption processes. UCNPs have some unique photophysical properties including large anti-Stokes shift, strong penetration into biological tissues, resistance to photobleaching, low background fluorescence, great chemical stability and low toxicity, therefore, they draw great attention and provide a variety of possibilities for sensing detection, bioimaging, and bioanalysis, and promoting the development of fluorescently labeled probes. In this review, the synthesis methods and surface functionalization strategies of UCNPs were summarized, also the recent progress of UCNPs on food safety detection was reviewed. Finally, the challenges faced by UCNPs and the opportunities for future development were discussed.
- Upconversion nanoparticles,
- Synthesis,
- Functionalization,
- Food safety,
- Review
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