Citation: WEI Feng, HAN Xiao-Jun. Nanozymes and Their Application Progress in Biomedical Detection[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(4): 581-592. doi: 10.19756/j.issn.0253-3820.201491 shu

Nanozymes and Their Application Progress in Biomedical Detection

WEI Feng ,
HAN Xiao-Jun ^,

State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China

Corresponding author: HAN Xiao-Jun, hanxiaojun@hit.edu.cn
Received Date: 14 August 2020
Revised Date: 1 December 2020

Fund Project: Supported by the National Key R&D Program of China (No.2016YFC0401104), the Harbin Distinguished Young Scholars Fund (No.2017RAYXJ024), and the State Key Laboratory of Urban Water Resource and Environment (Harbin Institute of Technology) (No.2020DX03).

As a kind of biocatalyst with high specificity, natural enzymes can be applied in recognition and detection by selective catalysis. However, the high cost and easy inactivation limit their practical applications. Nanozyme is a kind of nanomaterial which can mimic enzyme-like properties via the instinct ability, with many advantages such as low cost, stable performance and wide applications. The biomedical detection based on nanozymes with high sensitivity, excellent specificity and low limit of detection is promising. In this paper, several main types of nanozymes were summarized, followed by the introduction of their research progress in biomedical detection. The outlook of nanozymes in biomedical detection was also proposed at the end of this paper.
- Nanozymes,
- Biosensing,
- Enzyme-linked immunosorbent assay,
- Biomedical detection,
- Review
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