新型冠状病毒SARS-CoV-2核酸检测技术平台的研究进展

盛楠 马雪萍 逄淑云 宋沁馨 邹秉杰 周国华

引用本文: 盛楠,  马雪萍,  逄淑云,  宋沁馨,  邹秉杰,  周国华. 新型冠状病毒SARS-CoV-2核酸检测技术平台的研究进展[J]. 分析化学, 2020, 48(10): 1279-1287. doi: 10.19756/j.issn.0253-3820.201259 shu
Citation:  SHENG Nan,  MA Xue-Ping,  PANG Shu-Yun,  SONG Qin-Xin,  ZOU Bing-Jie,  ZHOU Guo-Hua. Research Progress of Nucleic Acid Detection Technology Platforms for New Coronavirus SARS-CoV-2[J]. Chinese Journal of Analytical Chemistry, 2020, 48(10): 1279-1287. doi: 10.19756/j.issn.0253-3820.201259 shu

新型冠状病毒SARS-CoV-2核酸检测技术平台的研究进展

  • 基金项目:

    本文系国家自然科学基金项目(Nos.61871403,81703474,81673390)、江苏省青年医学人才项目(No.QNRC2016889)和江苏省自然科学基金项目(No.BK20180292)资助

摘要: 新型冠状病毒(SARS-CoV-2)已蔓延至全球,严重威胁人类的健康。SARS-CoV-2传染性强、潜伏期长,且存在无症状感染者,因此,准确检测SARS-CoV-2对疫情防控至关重要。核酸检测技术在防控工作中发挥了举足轻重的作用,目前已开发出多种用于SARS-CoV-2核酸检测的方法,有些方法已被开发成试剂盒应用于临床检测。然而,这些方法原理各异,检测平台也不同,因此,选择合适的SARS-CoV-2核酸检测方法对疫情防控至关重要。本文介绍了目前核酸检测方法的原理与技术平台,比较了各方法的优缺点,明确了各类方法的应用范围,以期为选择合适的SARS-CoV-2核酸检测方法提供参考,对今后开发类似SARS-CoV-2的病原体检测方法提出展望。

English


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  • 收稿日期:  2020-05-06
  • 修回日期:  2020-08-06
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