基于高效液相色谱-气相色谱联用技术的矿物油分析研究进展

武彦文 李冰宁 刘玲玲 欧阳杰

引用本文: 武彦文, 李冰宁, 刘玲玲, 欧阳杰. 基于高效液相色谱-气相色谱联用技术的矿物油分析研究进展[J]. 分析化学, 2021, 49(3): 341-349. doi: 10.19756/j.issn.0253-3820.201134 shu
Citation:  WU Yan-Wen,  LI Bing-Ning,  LIU Ling-Ling,  OUYANG Jie. Research Progress of Analysis of Mineral Oil Hydrocarbons Using On-Line High Performance Liquid Chromatography Coupled with Gas Chromatography[J]. Chinese Journal of Analytical Chemistry, 2021, 49(3): 341-349. doi: 10.19756/j.issn.0253-3820.201134 shu

基于高效液相色谱-气相色谱联用技术的矿物油分析研究进展

    通讯作者: 武彦文,E-mail:wu_yanwen@163.com
  • 基金项目:

    北京市自然科学基金项目(No.2182020)和北京市科学技术研究院改革与发展经费培育类项目(No.PY2020JC38)资助。

摘要: 近年来,利用高效液相色谱-气相色谱联用技术(HPLC-GC)分析矿物油的研究发展迅速。矿物油源于石油与合成油,是涵盖一定碳数范围的碳氢化合物,主要分为烷烃和芳烃两大类。矿物油可通过多种途径迁移至食品和环境中,影响人类健康,然而其分析检测面临较大挑战。HPLC-GC (配备氢火焰离子化检测器)通过将净化、分离与检测相结合,很好地解决了矿物油分析中的选择性和灵敏度等问题。该技术的核心是通过保留间隙、Y形件接口和溶剂蒸气排出实现了GC大体积进样,将常规HPLC的洗脱流分全部转移至GC分析,将矿物油的分析灵敏度提高了两个数量级以上;同时避免了分析过程的污染引入,保证了分析的重现性和准确度。本文详细阐述了HPLC-GC的发展历程以及HPLC与GC分析条件的相互匹配,评述了基于HPLC-GC联用技术的干扰物去除与矿物油富集方法,并对HPLC-GC在矿物油分析中应用前景和发展趋势进行了展望。

English


    1. [1]

      European Food Safety Authority (EFSA). EFSA J., 2012, 10(6):2704.

    2. [2]

      BIEDERMANN M, GROB K. J. Chromatogr. A, 2012, 1255:56-75.

    3. [3]

      MORET S, BARP L, GROB K, CONTE L S. Food Chem., 2011, 129:1898-1903.

    4. [4]

      MORET S, BARP L, PURCARO G, CONTE L S. J. Chromatogr. A, 2012, 1243:1-5.

    5. [5]

      FISELIER K, GRUNDBÖCK F, SCHÖN K, KAPPENSTEIN O, PFAFF K, HUTZLER C, LUCH A, GROB K. J. Chromatogr. A, 2013, 1271:192-200.

    6. [6]

      MAJORS R E. J. Chromatogr. Sci., 1980, 18(10):571-579.

    7. [7]

      GROB K. On-line Coupled LC-GC. Hüthig, Heidelberg, 1991:10.

    8. [8]

      GROB K, FROHLICH D, SCHILLING B, NEUKOM H P, NAGELI P. J. Chromatogr. A, 1984, 295:55-61.

    9. [9]

      BIEDERMANN M, GROB K, MEIER W. J. High Resolut. Chromatogr., 1989, 12:591-598.

    10. [10]

      BOSELLI E, GROLIMUND B, GROB K. J. High Resolut. Chromatogr., 1998, 21:355-362.

    11. [11]

      BIEDERMANN M, GROB K. J. Chromatogr. A, 2013, 1281:106-114.

    12. [12]

      GROB K, BIEDERMANN M. J. Chromatogr. A, 1996, 750:11-23.

    13. [13]

      BOSELLI E, GROB K, LERCKER G. J. High Resolut. Chromatogr., 1999, 22:149-152.

    14. [14]

      GROB K, SCHMARR H G, MOSANDL A. J. High Resolut. Chromatogr., 1989, 12:375-382.

    15. [15]

      GROB K. J. Chromatogr. A, 2000, 892:407-420.

    16. [16]

      DUGO P, DUGO G, MONDELLO L. LC-GC Eur., 2003, 16(12A):35-43.

    17. [17]

      BIEDERMANN M, GROB K. J. Chromatogr. A, 2009, 1216:8652-8658.

    18. [18]

      PURCARO G, ZOCCALI M, TRANCHIDA P Q, BARP L, MORET S, CONTE L, DUGO P, MONDELLO L. Anal. Bioanal. Chem., 2013, 405:1077-1084.

    19. [19]

      DIN EN 16995-2017, Foodstuffs-Vegetable Oils and Foodstuff on Basis of Vegetable Oils-Determination of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) with On-line HPLC-GC-FID Analysis. British Standard.

    20. [20]

      BRATINOVA S, HOEKSTRA E (Editors). Luxembourg:Publications Office of the European Union, 2019, ISBN 978-92-76-00172-0.

    21. [21]

      DIN SPEC 5010:2018-05, Testing of Paper and Board-Determination of the Transfer of Mineral oil Hydrocarbons from Food Contact Material Manufactured with Portions of Recycled Pulp.

    22. [22]

      ISO 17780:2015, Animal and Vegetable Fats and Oils-Determination of Aliphatic Hydrocarbons in Vegetable Oils.

    23. [23]

      BENNETT B, LARTER S R. Anal. Chem. 2000, 72:1039-1044.

    24. [24]

      BIEDERMANN M, MUNOZ C, GROB K. J. Chromatogr. A, 2017, 1521:140-149.

    25. [25]

      BIEDERMANN M, GROB K. J. Chromatogr. A, 2012, 1255:76-99.

    26. [26]

      LIU Ling-Ling, WU Yan-Wen, LI Bing-Ning, WANG Yu, YANG Yi-Fan, ZU Wen-Chuan, WANG Xin-Xin. Chin. J. Anal. Chem., 2016, 44(9):1419-1424. 刘玲玲, 武彦文, 李冰宁, 汪雨, 杨一帆, 祖文川, 王欣欣. 分析化学, 2016, 44(9):1419-1424.

    27. [27]

      FISELIER K, FIORINI D, GROB K. Anal. Chim. Acta, 2009, 634:96-101.

    28. [28]

      FISELIER K, FIORINI D, GROB K. Anal. Chim. Acta, 2009, 634:102-109.

    29. [29]

      FISELIER K, GROB K. Eur. Food Res. Technol., 2009, 229:679-688.

    30. [30]

      ZURFLUH M, BIEDERMANN M, GROB K. J. Verbr. Lebensm., 2014, 9:61-69.

    31. [31]

      BROER W. Automated Solutions for the Determination of Contaminants in Food-from Sample Prep to Analysis. 9th International Symposium on Recent Advances in Food Analysis, Pague, Czech Republic, 2019, Nov 5th-8th, 59.

    32. [32]

      MORET S, GROB K, CONTE L S. J. Chromatogr. A, 1996, 750:361-368.

    33. [33]

      ZOCCALI M, BARP L, BECCARIA M, SCIARRONE D, PURCARO G, MONDELLO L. J. Sep. Sci., 2016, 39:623-631.

    34. [34]

      BIEDERMANN M, FISELIER K, GROB K. J. Agric. Food Chem., 2009, 57:8711-8721.

    35. [35]

      NESTOLA M, SCHMIDT T C. J. Chromatogr. A, 2017, 1505:69-76.

    36. [36]

      VAN HEYST A, VANLANCKER M, VERCAMMEN J, HOUWE K, MERTENS B, ELSKENS M, VAN HOECK E. Food Add. Contam. A, 2018, 35(6):2062-2075.

    37. [37]

      KOSTER S, VARELA J, STADLER R H, MOULIN J, CRUZ-HERNANDEZ C, HIELSCHER J, LESUEUR C, ROÏZ J, SIMIAN H. Food Add. Contam. A, 2020, 37(1):69-83.

    38. [38]

      BIEDERMANN M, MUNOZ C, GROB K. J. Chromatogr. A, 2020, 1624:461236.

    39. [39]

      BIEDERMANN-BREM S, KASPRICK N, SIMAT T J, GROB K. Food Add. Contam. A, 2012, 29(3):449-460.

    40. [40]

      ZHANG S C, LIU L L, LI B N, XIE Y Q, OUYANG J, WU Y W. Food Add. Contam. A, 2019, 36(8):1261-1272.

    41. [41]

      LOMMATZSCH M, BIEDERMANN M, SIMAT T J, GROB K. J. Chromatogr. A, 2015, 1402:94-101.

    42. [42]

      LOMMATZSCH M, BIEDERMANN M, GROB K, SIMAT T J. Food Add. Contam. A, 2016, 33(3):473-488.

    43. [43]

      European Food Safety Authority (EFSA), Arcella D, Baert K, Binaglia M. Rapid Risk Assessment on the Possible Risk for Public Health Due to the Contamination of Infant Formula and Follow-on Formula by Mineral Oil Aromatic Hydrocarbons (MOAH). EFSA Supporting Publicatons, 2019, EN-1741.

    44. [44]

      BIEDERMANN M, GROB K. J. Sep. Sci., 2009, 32:3726-3737.

    45. [45]

      BIEDERMANN M, GROB K. J. Chromatogr. A, 2015, 1375:146-153.

    46. [46]

      ZOCCALI M, TRANCHIDA P Q, MONDELLO L. Anal. Chim. Acta, 2019, 1048:221-226.

    47. [47]

      KOCH M, BECKER E, PÄCH M, KVHN S, KIRCHHOFF E. J. Sep. Sci. 2020, 43(6):1089-1099.

    48. [48]

      PURCARO G, TRANCHIDA P Q, BARP L, MORET S, CONTE L S, MONDELLO L. Anal. Chim. Acta, 2013, 773:97-104.

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  • 收稿日期:  2020-03-16
  • 修回日期:  2020-09-22
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