分子印迹光子晶体阵列传感器的构建及其对双酚A和双氰胺的检测

引用本文: 张鑫, 李彦松, 韩睿, 蒋艳艳, 刘哲涵. 分子印迹光子晶体阵列传感器的构建及其对双酚A和双氰胺的检测[J]. 分析化学, 2020, 48(3): 389-395. doi: 10.19756/j.issn.0253-3820.191684 shu

Citation: ZHANG Xin, LI Yan-Song, HAN Rui, JIANG Yan-Yan, LIU Zhe-Han. Construction of Molecularly Imprinted Photonic Crystal Sensor for Detection of Bisphenol A and Dicyandiamide[J]. Chinese Journal of Analytical Chemistry, 2020, 48(3): 389-395. doi: 10.19756/j.issn.0253-3820.191684 shu

分子印迹光子晶体阵列传感器的构建及其对双酚A和双氰胺的检测

张鑫 ^1, ,
李彦松 ^1, ,
韩睿 ^1, ,
蒋艳艳 ^1, ,
刘哲涵 ^2,

1.
南阳师范学院, 生命与科学技术学院, 南阳 473061;
2.
北京理工大学, 生命学院, 北京 100081
基金项目:
本文系河南省教育厅重点研究项目（No.20A180021）和南阳师范学院科研项目（No.2019ZX011）资助

摘要: 将分子印迹技术与光子晶体材料结合，构建了基于反蛋白石结构分子印迹光子晶体聚合物（MIPPs）的阵列传感器，用于微量双酚A （BPA）和双氰胺（DCD）的特异识别检测。对分子印迹聚合体系、模板分子洗脱条件进行了优化，当单体与模板分子摩尔比分别为1∶2和1∶4时，制备的BPA和DCD MIPPs的吸附效果最好，衍射峰位移最大。通过吸附动力学和吸附等温线实验考察了构建的传感器阵列的吸附性能。结果表明，构建的MIPPs传感器对BPA和DCD的响应时间分别为2.5和4.0 min，衍射峰位移量与BPA和DCD在其浓度分别为0.1~5.0 μg/L和0.1~10.0 μg/L范围时具有良好的线性关系，最大衍射峰位移量分别为39和31 nm，检出限分别为0.051和0.038 μg/L；而非印迹光子晶体膜的衍射峰位移不明显，表明制备的MIPPs阵列具有选择特异性。实际样品测定结果表明，此MIPPs阵列传感器对实际样品中的目标物有明显的光学信号响应，可以快速、灵敏、选择性地检测环境水样中的目标分析物。

关键词:

English

Construction of Molecularly Imprinted Photonic Crystal Sensor for Detection of Bisphenol A and Dicyandiamide

1.
School of Life Science and Technology, Nanyang Normal University, Nanyang 473061, China;
2.
School of Life Science, Beijing Institute of Technology, Beijing 100081, China
Received Date: 19 November 2019
Revised Date: 02 January 2020
Fund Project:
This work was supported by the Key Scientific Research Projects of Higher Education Institutions in Henan Province, China (No. 20A180021) and the Scientific Research Projects of Nanyang Normal University (No. 2019ZX011).

Abstract: The molecular imprinting technique and photonic crystal materials were combined to construct an array of sensors based on inverse-opal structure molecularly imprinted photonic crystal film (MIPPs) for the determination of trace amounts of bisphenol A (BPA) and dicandiamide (DCD) in environmental water samples. The polymerization system of molecularly imprinting and elution system were optimized. The best adsorptive property and the maximum diffraction peak of the prepared BPA and DCD molecularly imprinted photonic crystal film were achieved when the ratios of monomer and template molecules were 1:2 and 1:4, respectively. The performance of the MIPPs sensor array was investigated by adsorption kinetics and adsorption isotherm experiments. Experimental results showed that the response time of the prepared MIPPs for BPA and DCD were 2.5 and 4.0 min, respectively. In the concentration range of 0.1-5.0 μg/L and 0.1-10.0 μg/L, the diffraction peak displacement of MIPPs for BPA and DCD was obvious, the maximum displacement was 39 and 31 nm, and the limits of detection were 0.051 μg/L and 0.038 μg/L(S/N=3), respectively. However, the diffraction peak displacement of the non-imprinted photonic crystal film was not obvious, which indicated that the prepared MIPPs had selective specificity. The real sample test results showed that the development MIPPs had an obvious optical signal response to the target molecules, which could be used for the rapid, sensitive and selective detection of the residual BPA and DCD in environmental waters.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

分子印迹光子晶体阵列传感器的构建及其对双酚A和双氰胺的检测

English

Construction of Molecularly Imprinted Photonic Crystal Sensor for Detection of Bisphenol A and Dicyandiamide

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

分子印迹光子晶体阵列传感器的构建及其对双酚A和双氰胺的检测

English

Construction of Molecularly Imprinted Photonic Crystal Sensor for Detection of Bisphenol A and Dicyandiamide

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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