基于谷胱甘肽修饰的金纳米簇选择性检测铜离子

安春 杜佩瑶 张振 卢小泉

引用本文: 安春,  杜佩瑶,  张振,  卢小泉. 基于谷胱甘肽修饰的金纳米簇选择性检测铜离子[J]. 分析化学, 2020, 48(3): 355-362. doi: 10.19756/j.issn.0253-3820.191668 shu
Citation:  AN Chun,  DU Pei-Yao,  ZHANG Zhen,  LU Xiao-Quan. Rapid and Highly Selective Detection of Copper Ion with Glutathione-capped Gold Nanoclusters[J]. Chinese Journal of Analytical Chemistry, 2020, 48(3): 355-362. doi: 10.19756/j.issn.0253-3820.191668 shu

基于谷胱甘肽修饰的金纳米簇选择性检测铜离子

  • 基金项目:

    本文系国家自然科学基金项目(Nos.21575115,21705117)资助

摘要: 建立了一种基于谷胱甘肽(GSH)包裹的金纳米簇(AuNCs)高选择性检测水中和血清中铜离子(Cu2+)的方法。Cu2+与AuNCs配体上的氨基(-NH2)和羧基(-COOH)发生配位作用,阻断配体-金属间或配体-金属-金属间的电荷转移,导致AuNCs的荧光猝灭; EDTA与Cu2+具有更强的配位作用,可将Cu2+从AuNCs表面移除,使AuNCs荧光恢复。本研究中,AuNCs发射红色荧光,避免了复杂生物基质背景荧光的干扰,在pH=5.5的条件下,可快速、灵敏、高选择性地检测Cu2+,检出限为23 nmol/L。血清和水样中Cu2+的加标回收率为96.2%~100.1%。本方法在药物分析、环境监测、临床诊断等方面具有广阔的应用前景。

English


    1. [1]

      Chen J, Chen H Y, Wang T S, Li J F, Wang J, Lu X Q. Anal. Chem.,2019,91(7):4331-4336

    2. [2]

      Sedgwick A C, Wu L L, Han H H, Bull S D, He X P, James T D, Sessler J L, Tang B Z, Tian H, Yoon J Y. Chem. Soc. Rev.,2018,47(23):8842-8880

    3. [3]

      Festa R A, Thiele D J. Curr. Biol.,2011,21(21):R877-R883

    4. [4]

      Georgopoulos P G, Roy A, Yonone-Lioy M J, Opiekun R E, Lioy P J. J. Toxicol. Environ. Health B,2001,4(4):341-394

    5. [5]

      Cotruvo J A, Aron A T, Ramos-Torres K M, Chang C J. Chem. Soc. Rev.,2015,44(13):4400-4414

    6. [6]

      Silva E L, Roldan P D S, Giné M F. J. Hazard. Mater.,2009,171(1-3):1133-1138

    7. [7]

      Liu A C, Chen D C, Lin C C, Chou H H, Chen C H. Anal. Chem.,1999,71(8):1549-1552

    8. [8]

      Maréchal C N, Télouk P, Albarède F. Chem. Geol.,1999,156(1-4):251-273

    9. [9]

      Lin T W, Huang S D. Anal. Chem.,2001,73(17):4319-4325

    10. [10]

      Adinarayana B, Thomas A P, Yadav P, Kumar A, Srinivasan A. Angew. Chem. Int. Ed.,2016,55(3):969-973

    11. [11]

      Pathan S, Jalal M, Prasad S, Bose S. J. Mater. Chem. A,2019,7(14):8510-8520

    12. [12]

      Dong Y Q, Wang R X, Li G L, Chen C Q, Chi Y W, Chen G N. Anal. Chem.,2012,84(14):6220-6224

    13. [13]

      Zhang L B, Wang E K. Nano Today,2014,9(1):132-157

    14. [14]

      You J G, Lu C Y, Kumar A S K, Tseng W L. Nanoscale,2018,10(37):17691-17698

    15. [15]

      Meng J, Shuang E, Wei X, Chen X W, Wang J H. ACS Appl. Mater. Interfaces,2019,11(23):21150-21158

    16. [16]

      Xie Y, Xianyu Y L, Wang N X, Yan Z Y, Liu Y, Zhu K, Hatzakis N S, Jiang X Y. Adv. Funct. Mater.,2018,28(14):1702026

    17. [17]

      Zang J C, Li C A, Zhou K, Dong H S, Chen B, Wang F D, Zhao G H. Anal. Chem.,2016,88(20):10275-10283

    18. [18]

      Luo Z T, Yuan X, Yu Y, Zhang Q B, Leong D T, Lee J Y, Xie J P. J. Am. Chem. Soc.,2012,134(40):16662-16670

    19. [19]

      Yuan Z Q, Cai N, Du Y, He Y, Yeung E S. Anal. Chem.,2014,86(1):419-426

    20. [20]

      Yu M Q, Zhu Z G, Wang H, Li L Y, Fu F, Song Y, Song E Q. Biosens. Bioelectron.,2017,91:143-148

    21. [21]

      Roy S, Palui G, Banerjee A. Nanoscale,2012,4(8):2734-2740

    22. [22]

      Yuan X, Yeow T J, Zhang Q B, Lee J Y, Xie J P. Nanoscale,2012,4(6):1968-1971

    23. [23]

      Li X J, Li Y, Liu A Y, Tan Y H, Ling J, Ding Z T, Cao Q E. Spectrochim. Acta A,2020,224:117472

    24. [24]

      Zhang C X, Sun X Y, Li J, Liu Y N. Nanoscale,2013,5(14):6261-6264

    25. [25]

      Deng H H, Shi X Q, Wang F F, Peng H P, Liu A L, Xia X H, Chen W. Chem. Mater.,2017,29(3):1362-1369

    26. [26]

      Zhou S C, Zhang M, Yang F Y, Wang F, Wang C Y. J. Mater. Chem. C,2017,5(9):2466-2473

    27. [27]

      Jia X F, Li J, Wang E K. Small,2013,9(22):3873-3879

    28. [28]

      Zhang J, Yuan Y, Wang Y, Sun F F, Liang G L, Jiang Z, Yu S H. Nano Res.,2015,8(7):2329-2339

    29. [29]

      Peng H P, Jian M L, Huang Z N, Wang W J, Deng H H, Wu W H, Liu A L, Xia X H, Chen W. Biosens. Bioelectron.,2018,105:71-76

    30. [30]

      GB/5749-2006, Standards for Drinking Water Quality. National Standards of the People's Republic of China生活饮用水卫生标准.中华人民共和国国家标准. GB/5749-2006

    31. [31]

      Yang Y Z, Xiao N, Cen Y Y, Chen J R, Liu S G, Shi Y, Fan Y Z, Li N B, Luo H Q. Spectrochim. Acta B,2019,223:117300

    32. [32]

      Li L N, Shen S S, Lin R Y, Bai Y, Liu H W. Chem. Commun.,2017,53(72):9986-9989

    33. [33]

      Zou C C, Foda M F, Tan X C, Shao K, Wu L, Lu Z C, Bahlol H S, Han H Y. Anal. Chem.,2016,88(14):7395-7403

    34. [34]

      Qing Z H, Zhu L X, Yang S, Cao Z, He X X, Wang K M, Yang R H. Biosens. Bioelectron.,2016,78:471-476

    35. [35]

      Zhao H M, Wen X P, Li W Y, Li Y Q, Yin C X. J. Mater. Chem. B,2019,7(13):2169-2176

    36. [36]

      Sun J, Yang F, Zhao D, Yang X R. Anal. Chem.,2014,86(15):7883-7889

    37. [37]

      Sun J, Yang F, Zhao D, Chen C X, Yang X R. ACS Appl. Mater. Interfaces,2015,7(12):6860-6866

    38. [38]

      Xu S H, Gao T, Feng X Y, Mao Y N, Liu P P, Yu X J, Luo X L. J. Mater. Chem. B,2016,4(7):1270-1275

  • 加载中
计量
  • PDF下载量:  1
  • 文章访问数:  21
  • HTML全文浏览量:  1
文章相关
  • 收稿日期:  2019-11-13
  • 修回日期:  2020-01-03
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

/

返回文章