Citation: FANG Sui, LI Zhi-Ming, XU Jiang, WANG Wei, ZHAI Li-Hua, DENG Hu, WEI Guan-Yi. An Efficient Isotopic Dilution Method and Its Application in Tracing Technology[J]. Chinese Journal of Analytical Chemistry, ;2020, 48(11): 1542-1549. doi: 10.19756/j.issn.0253-3820.191479 shu

An Efficient Isotopic Dilution Method and Its Application in Tracing Technology

Northwest Institute of Nuclear Technology, Xi'an 710024, China

Corresponding author: WEI Guan-Yi, Weiguanyi@nint.cn
Received Date: 15 August 2019
Revised Date: 14 September 2020

In conventional isotopic dilution method, when target isotope in a sample is influenced by the tracing material, it should be measured includes not only the isotope ratios of the mixture of dilution and sample, but also that of the original sample. In case that sample is insufficient, or measuring time is limited, the isotope dilute method meets its embarrassment. In this study, an efficient quantitative isotopic dilution method was provided, in which the measurement of the isotope ratios in the sample was unnecessary. This method had particularly advantage on reducing sample consumption, simplifying the measurement procedure and decreasing the influence of memory effect, which greatly improved the efficiency of the measurement. The six measurements showed that xenon standard gas was used to verify its applicability, which provided a bias of less than 1% to the nominal value and a relative standard deviation (RSD) of 0.4%. The measurement result was completely consistent with the value of conventional isotope dilution. In tracing experiment with ¹²⁸Xe, despite of the interference of natural xenon, ¹²⁸Xe of tracer was precisely determined. The diffusion curve which was drawn by ¹²⁸Xe, also accorded with the rule of gas diffusion in the closed space. This method was suitable only for elements that with three or more isotopes.
- Isotope dilution,
- Quantification,
- Efficient,
- Tracer
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
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