一种快速同位素稀释定量方法及其在示踪方面的应用

引用本文: 方随, 李志明, 徐江, 汪伟, 翟利华, 邓虎, 韦冠一. 一种快速同位素稀释定量方法及其在示踪方面的应用[J]. 分析化学, 2020, 48(11): 1542-1549. doi: 10.19756/j.issn.0253-3820.191479 shu

Citation: FANG Sui, LI Zhi-Ming, XU Jiang, WANG Wei, ZHAI Li-Hua, DENG Hu, WEI Guan-Yi. An Efficient Isotopic Dilution Method and Its Application in Tracing Technology[J]. Chinese Journal of Analytical Chemistry, 2020, 48(11): 1542-1549. doi: 10.19756/j.issn.0253-3820.191479 shu

一种快速同位素稀释定量方法及其在示踪方面的应用

西北核技术研究所, 西安 710024

通讯作者: 韦冠一,Weiguanyi@nint.cn

基金项目:
本文系科技部重大仪器专项项目（2012YQ250003）资助

摘要: 同位素稀释法定量分析中，当待测样品中某一目标同位素的丰度被示踪剂影响而不能保持天然丰度时，需要测量样品中各同位素的丰度比。在待测样品量或测量时间有限时，常规同位素稀释法的应用受到局限。为了降低样品消耗量、简化测量步骤、减小记忆效应影响、提高测量效率，本研究建立了一种可省略待测样品丰度比测量环节的快速同位素稀释定量方法。基于物质的量守恒原理，通过关联的运算，得到待测样品后，只需进行一次添加同位素稀释剂后混合样品的丰度比测量即可完成目标同位素的定量分析。以天然丰度Xe标准气体作为模拟样品，6次测量值与标称值的相对偏差均小于1%，相对标准偏差（RSD）为0.4%，与使用常规同位素稀释法得到的测量结果完全相符。此外，以¹²⁸Xe作为示踪同位素，得到的示踪同位素扩散曲线符合气体在封闭空间的扩散规律。本方法适用于有3种或更多稳定同位素的元素，既保证了测量结果的准确性，又可缩短分析时间，减少样品消耗量。

关键词:

同位素稀释
/ 定量
/ 快速
/ 示踪

English

An Efficient Isotopic Dilution Method and Its Application in Tracing Technology

Northwest Institute of Nuclear Technology, Xi'an 710024, China

Corresponding author: WEI Guan-Yi, Weiguanyi@nint.cn

Received Date: 15 August 2019
Revised Date: 14 September 2020

Abstract: In conventional isotopic dilution method, when target isotope in a sample is influenced by the tracing material, it should be measured includes not only the isotope ratios of the mixture of dilution and sample, but also that of the original sample. In case that sample is insufficient, or measuring time is limited, the isotope dilute method meets its embarrassment. In this study, an efficient quantitative isotopic dilution method was provided, in which the measurement of the isotope ratios in the sample was unnecessary. This method had particularly advantage on reducing sample consumption, simplifying the measurement procedure and decreasing the influence of memory effect, which greatly improved the efficiency of the measurement. The six measurements showed that xenon standard gas was used to verify its applicability, which provided a bias of less than 1% to the nominal value and a relative standard deviation (RSD) of 0.4%. The measurement result was completely consistent with the value of conventional isotope dilution. In tracing experiment with ¹²⁸Xe, despite of the interference of natural xenon, ¹²⁸Xe of tracer was precisely determined. The diffusion curve which was drawn by ¹²⁸Xe, also accorded with the rule of gas diffusion in the closed space. This method was suitable only for elements that with three or more isotopes.

Key words:

1. [1]
  Jarvis K E, Gray A L, Houk R S. Handbook of Inductively Coupled Plasma Mass Spectrometry, Translated by YIN Ming, LI Bing. Beijing:Atomic Energy Press,1997:194 Jarvis K E, Gray A L, Houk R S.电感耦合等离子体质谱手册.尹明, 李冰译. 北京:原子能出版社, 1997:194
2. [2]
  HUANG Da-Feng, LUO Xiu-Quan, LI Xi-Bin, DENG Zhong-Guo. Technology and Application of Isotope Mass. Beijing:Chemical Industry Press,2006:311 黄达峰, 罗修泉, 李喜斌, 邓中国.同位素质谱技术与应用.北京:化学工业出版社, 2006:311
3. [3]
  ZHAO Mo-Tian, CAO Yong-Ming, CHEN Gang, JIANG Shan. Conspectus of Inorganic Mass. Beijing:Chemical Industry Press,2006:322 赵墨田, 曹永明, 陈刚, 姜山.无机质谱概论.北京:化学工业出版社, 2006:322
4. [4]
  YANG Chao-Yong, ZHUANG Zhi-Sha, GU Sheng, CHEN Fa-Rong, WU Xi-Hong, WANG Xiao-Ru. Journal of Instrumental Analysis,2001,20(2):87-92 杨朝勇, 庄峙厦, 谷胜, 陈发荣, 吴熙鸿, 王小如.分析测试学报,2001,20(2):87-92
5. [5]
  LIU Qing-Kai, XU Meng-Tian, MA Xian, LIU Tao, WANG Yun. Scientific and Technological Innovation,2019,(10):13-14 刘庆凯, 徐梦恬, 马贤, 刘涛, 王筠.科学技术创新,2019,(10):13-14
6. [6]
  TANG Suo-Han, LI Jin, MA Jian-Xiong, ZHAO Xin-Miao, ZHU Xiang-Kun. Chinese J. Anal. Chem., 2018,46(10):1618-1627 唐索寒, 李津, 马健雄, 赵新苗, 朱祥坤.分析化学,2018,46(10):1618-1627
7. [7]
  CHEN Xue, WANG Jun, FENG Liu-Xing, YANG Xiao-Jing. Journal of Chinese Mass Spectrometry Society, 2016,37(1):31-36 陈雪, 王军, 冯流星, 杨晓进.质谱学报,2016,37(1):31-36
8. [8]
  LU Ya-Li, SUN Ai-Hua, HE Fu-Chu, JIANG Ying. Progress in Biochemistry and Biophysics,2013, 40(12):1201-1208 陆亚丽, 孙爱华, 贺福初, 姜颖.生物化学与生物物理进展,2013,40(12):1201-1208
9. [9]
  HUO Zhong-Zhong, FENG Liu-Xing, LI Hong-Mei, XIONG Jin-Ping. Chinese J. Anal. Chem.,2019,47(12):1931-1937 霍中中, 冯流星, 李红梅, 熊金平.分析化学,2019,47(12):1931-1937
10. [10]
  Sebastien G, Elodie D, Bruno D. J. Mass Spectrom.,2011,46(3):298-312
11. [11]
  Asai S, Hanzawa Y, Konda M, Suzuki D, Magara M, Kimura T, Ishihara R, Saito K, Yamada S, Hirota H. Talanta,2018,185:98-105
12. [12]
  Giusepponi D, Torquato P, Bartolini D, Piroddi M, Birringer M, Lorkowski S, Libetta C, Cruciani G, Moretti S, Saluti G, Galli F, Galarini R. Talanta,2017,170:552-561
13. [13]
  GUO Qing-Jun, YANG Wei-Dong, YU Ya. Bulletin of Mineralogy Petrology and Geochemistry,2000,7(3):193-196 郭庆军, 杨卫东, 余娅.矿物岩石地球化学通报,2000,7(3):193-196
14. [14]
  QU Wen-Jun, DU An-Dao, ZHAO Dun-Min. Chinese J. Anal. Chem.,2001,29(1):19-22 屈文俊, 杜安道, 赵敦敏.分析化学,2001,29(1):19-22
15. [15]
  Bollard J, Connelly J N, Bizzarro M. Meteoritics Planetary Sci.,2015,50(7):1197-1216
16. [16]
  Malinovsky D, Rodushkin I, Baxter D, Ohlander B. Anal. Chim. Acta,2002,463(1):111-124
17. [17]
  Junk S A, Pernicka E. Archaeometry,2003,45(2):313-331
18. [18]
  Tartese R, Anand M, Delhaye T. Am. Mineral., 2013,98(8/9):1477-1486
19. [19]
  Farley K A, Hurowitz J A, Asimow P D, Jacobson N S, Cartwright J A. Geochim. Cosmochim. Acta,2013,110:1-12
20. [20]
  LIU Fang, ZHU Li-Hong, TAN De-Can, LIU Yu-Fei, KANG Jin-Ting, ZHU Jian-Ming, WANG Gui-Qin, ZHANG Zhao-Feng. Journal of Chinese Mass Spectrometry Society,2016,37(4):310-317 刘芳, 祝丽红, 谭德灿, 刘峪菲, 康晋霆, 朱建明, 王桂琴, 张兆峰.质谱学报,2016,37(4):310-317
21. [21]
  LI Hai-Tao, WU Yan-You, ZHAO Li-Hua, ZHANG Kai-Yan, HANG Hong-Tao. Carsologica Sinica,2016,35(6):614-618 李海涛, 吴沿友, 赵丽华, 张开艳, 杭红涛.中国岩溶,2016,35(6):614-618
22. [22]
  WEI Guan-Yi, Goetz A, ZHANG Zi-Bin, LI Xue-Song, Gerken H. Journal of Chinese Mass Spectrometry Society,2004,25(Suppl.):11-12 韦冠一, Goetz A, 张子斌, 李雪松, Gerken H.质谱学报,2004,25(Suppl.):11-12
23. [23]
  ZHU Feng-Rong, DONG Hong-Bo, ZHOU Guo-Qing, LI Zhi-Ming, WAN Ke-You, YU Jiang, LI Mei. Journal of Chinese Mass Spectrometry Society,2004,25(Suppl.):163-165 朱凤蓉, 董宏波, 周国庆, 李志明, 万可友, 俞江, 李梅.质谱学报,2004,25(Suppl.):163-165
24. [24]
  ZHANG Zi-Bin, Goetz A, WEI Guan-Yi, LI Xue-Song, Gerken H, CHANG Yong-Fu. Journal of Chinese Mass Spectrometry Society,2004,25(Suppl.):194-204 张子斌, Goetz A, 韦冠一, 李雪松, Gerken H, 常永福.质谱学报,2004,25(Suppl.):194-204

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沈阳化工大学材料科学与工程学院沈阳 110142

一种快速同位素稀释定量方法及其在示踪方面的应用

通讯作者: 韦冠一,Weiguanyi@nint.cn

English

An Efficient Isotopic Dilution Method and Its Application in Tracing Technology

Corresponding author: WEI Guan-Yi, Weiguanyi@nint.cn

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

一种快速同位素稀释定量方法及其在示踪方面的应用

通讯作者: 韦冠一,Weiguanyi@nint.cn

English

An Efficient Isotopic Dilution Method and Its Application in Tracing Technology

Corresponding author: WEI Guan-Yi, Weiguanyi@nint.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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