Citation:
CHEN Zhong-Hui, CHEN Yu, WENG Ai-Bin, LUO Fang, GUO Long-Hua, QIU Bin, LIN Zhen-Yu, CHEN Guo-Nan. Research Progress of in Vivo Detection Methods for Gasotransmitter Hydrogen Sulfide[J]. Chinese Journal of Analytical Chemistry,
;2019, 47(10): 1572-1579.
doi:
10.19756/j.issn.0253-3820.191366
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The quantitative analysis for neurochemistry in living biosystems has drawn extensive attention, because the physiological active substance participates in the transmission of information and relates to physiology and pathology in the brain. Hydrogen sulfide (H2S), as the third gasotransmitter, plays a significant role in the neurophysiology and neuropathology in brain. In vivo detection of H2S will greatly promote the molecular mechanism in the physiology and pathology process. However, H2S have strong reducibility and volatility, and its properties are similar to those of sulfhydryl compounds in the brain. Therefore, selective separation and recognition of H2S from sulfhydryl compounds in the brain is the key scientific issue in the detection of H2S. Herein, the design principle and research progress of various types of H2S detection methods in recent year were reviewed, and an outlook for the future of H2S detection method was propected.
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Keywords:
- Hydrogen sulfide,
- In vivo detection methods,
- Review
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