Citation: YU Li-Xing, ZHAI Rui, GONG Xiao-Yun, XIE Jie, HUANG Ze-Jian, LIU Mei-Ying, JIANG You, DAI Xin-Hua, FANG Xiang, YU Xiao-Ping. Progress in DNA Tetrahedral Nanomaterials and Their Functionalization Research[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(11): 1742-1750. doi: 10.19756/j.issn.0253-3820.191274 shu

Progress in DNA Tetrahedral Nanomaterials and Their Functionalization Research

1.
College of Life Sciences, Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, China Jiliang University, Hangzhou 310018, China;
2.
Mass Spectrometry Engineering Technology Research Center, Center for Advanced Measurement Science, National Institute of Metrology, Beijing 100029, China

Received Date: 10 May 2019
Revised Date: 4 July 2019

Fund Project: This work was supported by the National Key Research and Development Program of China (No.2018YFF0212503) and the National Natural Science Foundation of China (No.21575132).

DNA tetrahedral nanomaterials have been widely used in the fields of biosensors, drug delivery, bioimaging and separation analysis because of their high stability, good biocompatibility and easy modification. Through different designs, specific functional molecules can be modified at DNA tetrahedral vertices, DNA tetrahedral cage structures, DNA double helix structures, or DNA tetrahedron arms. The advantages of the materials are well combined with the specific functions of the active molecules. This paper first reviewed the development of DNA nanotechnology, and then introduced four different functional modifications of DNA tetrahedron nanomaterials and their research status.
- DNA nanotechnology,
- DNA tetrahedron,
- Functionalization,
- Review
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沈阳化工大学材料科学与工程学院沈阳 110142