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Syntheses, Structures and Anticancer Activities of Three 4(3H)-Quinazolinone Cd(II) Complexes
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关键词:
- complex
- / 4(3H)-quinazolinone
- / anticancer
English
Syntheses, Structures and Anticancer Activities of Three 4(3H)-Quinazolinone Cd(II) Complexes
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Key words:
- complex
- / 4(3H)-quinazolinone
- / anticancer
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[1]
(1) Pavel, Z.; Mark, S.; Gao, X. H. Designing multifunctional quantum dots for bioimaging, detection, and drug delivery. Chem. Soc. Rev. 2010, 39, 4326–4354.(1) Pavel, Z.; Mark, S.; Gao, X. H. Designing multifunctional quantum dots for bioimaging, detection, and drug delivery. Chem. Soc. Rev. 2010, 39, 4326–4354.
-
[2]
(2) Sweigert, P.; Xu, Z. M.; Hong, Y. L.; Swavey, S. Nickel, copper, and zinc centered ruthenium-substituted porphyrins: effect of transition metals on photoinduced DNA cleavage and photoinduced melanoma cell toxicity. Dalton Trans. 2012, 41, 5201–5208.(2) Sweigert, P.; Xu, Z. M.; Hong, Y. L.; Swavey, S. Nickel, copper, and zinc centered ruthenium-substituted porphyrins: effect of transition metals on photoinduced DNA cleavage and photoinduced melanoma cell toxicity. Dalton Trans. 2012, 41, 5201–5208.
-
[3]
(3) Christopher, J. C.; Kenneth, N. R. Preface for the forum on imaging and sensing: probing and utilizing the elements of life for studying and improving health and society. Inorg. Chem. 2014, 53, 1791–1793.(3) Christopher, J. C.; Kenneth, N. R. Preface for the forum on imaging and sensing: probing and utilizing the elements of life for studying and improving health and society. Inorg. Chem. 2014, 53, 1791–1793.
-
[4]
(4) Fan, J. F.; Sun, D. K.; Yu, H. T.; Kerwin, S. M.; Hurley, L. H. Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. J. Med. Chem. 1995, 38, 408–424.(4) Fan, J. F.; Sun, D. K.; Yu, H. T.; Kerwin, S. M.; Hurley, L. H. Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. J. Med. Chem. 1995, 38, 408–424.
-
[5]
(5) Catherine, M. C.; Emilia, P.; Patrycja, N. S.; Arjan, W. G..; Rosario, S.; Paul, J. D. Discovery of a highly tumor-selective organometallic ruthenium(II)-arene complex. J. Med. Chem. 2014, 57, 3546–3558.(5) Catherine, M. C.; Emilia, P.; Patrycja, N. S.; Arjan, W. G..; Rosario, S.; Paul, J. D. Discovery of a highly tumor-selective organometallic ruthenium(II)-arene complex. J. Med. Chem. 2014, 57, 3546–3558.
-
[6]
(6) Mak, N. K.; Leung, C. Y.; Wei, X. Y.; Shen, X. L.; Wong, R. N.; Leungd, K. N.; Fung, M. C. Inhibition of RANTES expression by indirubin in influenza virus-infected human bronchial epithelial cells. Biochem. Pharm. 2004, 67, 167–174.(6) Mak, N. K.; Leung, C. Y.; Wei, X. Y.; Shen, X. L.; Wong, R. N.; Leungd, K. N.; Fung, M. C. Inhibition of RANTES expression by indirubin in influenza virus-infected human bronchial epithelial cells. Biochem. Pharm. 2004, 67, 167–174.
-
[7]
(7) Bekhit, A. A.; Habib, N. S.; EL-Din, A. Synthesis and antimicrobial evaluation of chalcone and syndrome derivatives of 4(3H)-quinazolinone. Boll. Chim. Farm. 2001, 140, 297–301.(7) Bekhit, A. A.; Habib, N. S.; EL-Din, A. Synthesis and antimicrobial evaluation of chalcone and syndrome derivatives of 4(3H)-quinazolinone. Boll. Chim. Farm. 2001, 140, 297–301.
-
[8]
(8) Li, S. X.; Liao, B. L.; Luo, P.; Jiang, Y. M. Synthesis, structures, fluorescence and anticancer activity of Co(II) and Ag(I) complexes with 4 (3H)–quinazolinone. Chin. J. Inorg. Chem. 2015, 2, 291–296.(8) Li, S. X.; Liao, B. L.; Luo, P.; Jiang, Y. M. Synthesis, structures, fluorescence and anticancer activity of Co(II) and Ag(I) complexes with 4 (3H)–quinazolinone. Chin. J. Inorg. Chem. 2015, 2, 291–296.
-
[9]
(9) Cao, S. L.; Feng, Y. P.; Jiang, Y. Y.; Liu, S. Y.; Ding, G. Y.; Li, R. T. Synthesis and in vitro antitumor activity of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains. Bioorg. Med. Chem. Lett. 2005, 15, 1915–1917.(9) Cao, S. L.; Feng, Y. P.; Jiang, Y. Y.; Liu, S. Y.; Ding, G. Y.; Li, R. T. Synthesis and in vitro antitumor activity of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains. Bioorg. Med. Chem. Lett. 2005, 15, 1915–1917.
-
[10]
(10) Liu, S. Y.; Liu, F.; Yu, X. Q.; Ding, G. Y.; Xu, P.; Gao, J.; Jiang, Y. Y. The 3D-QSAR analysis of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains on thymidylate synt hase. Bioorg. Med. Chem. 2006, 14, 1425–1430.(10) Liu, S. Y.; Liu, F.; Yu, X. Q.; Ding, G. Y.; Xu, P.; Gao, J.; Jiang, Y. Y. The 3D-QSAR analysis of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains on thymidylate synt hase. Bioorg. Med. Chem. 2006, 14, 1425–1430.
-
[11]
(11) Refaie, F. M.; Esmat, A. Y.; Gawad, S. M.; Ibrahim, A. M.; Mohamed, M. A. The antihyperlipidemic activities of 4(3H)-quinazolinone and two halogenated derivatives in rats. Lipids Health Dis. 2005, 4, 22–28.(11) Refaie, F. M.; Esmat, A. Y.; Gawad, S. M.; Ibrahim, A. M.; Mohamed, M. A. The antihyperlipidemic activities of 4(3H)-quinazolinone and two halogenated derivatives in rats. Lipids Health Dis. 2005, 4, 22–28.
-
[12]
(12) Habib, N. S.; Ismail, K. A.; EI-tombary, A. A.; Abdel, A. T. Antilipidemic agents, Part. IV: synthesis and antilipidemic testing of some heterocyclic derivatives of hexadecyl and cyclohexyl hemisuccinate esters. Pharmazie 2000, 55, 495–499.(12) Habib, N. S.; Ismail, K. A.; EI-tombary, A. A.; Abdel, A. T. Antilipidemic agents, Part. IV: synthesis and antilipidemic testing of some heterocyclic derivatives of hexadecyl and cyclohexyl hemisuccinate esters. Pharmazie 2000, 55, 495–499.
-
[13]
(13) Xie, Q. F.; Gao, P. Z.; Chen, Y. M. Synthesis, crystal structure and anti-tumor activity in vitro of a hydrazone Schiff base and its Cd(II) complex. Chin.J. Inorg. Chem. 2014, 10, 2382–2388.(13) Xie, Q. F.; Gao, P. Z.; Chen, Y. M. Synthesis, crystal structure and anti-tumor activity in vitro of a hydrazone Schiff base and its Cd(II) complex. Chin.J. Inorg. Chem. 2014, 10, 2382–2388.
-
[14]
(14) Huang, Q. Y.; Zheng, Z. B.; Diao, Y. P. Synthesis, characterization and anticancer activity of a Cd(II) complex with in situ formation of (E)-1-(5-chloro-2-hydroxy-benzylideneamino)-pyrrolidin-2-one ligand. J. Mol. Stru. 2015, 1088, 118–122.(14) Huang, Q. Y.; Zheng, Z. B.; Diao, Y. P. Synthesis, characterization and anticancer activity of a Cd(II) complex with in situ formation of (E)-1-(5-chloro-2-hydroxy-benzylideneamino)-pyrrolidin-2-one ligand. J. Mol. Stru. 2015, 1088, 118–122.
-
[15]
(15) Nuria, A.; Rosario, A.; Miguel, N. Synthesis, structure and biological activity of a new and efficient Cd(II)-uracil derivative complex system for cleavage of DNA. J. Biol. Inorg. Chem. 2005, 10, 924–934.(15) Nuria, A.; Rosario, A.; Miguel, N. Synthesis, structure and biological activity of a new and efficient Cd(II)-uracil derivative complex system for cleavage of DNA. J. Biol. Inorg. Chem. 2005, 10, 924–934.
-
[16]
(16) Dolomanov, O. V.; Bourhis, L. J.; Gildea, R. J.; Howard, J. A. K.; Puschmann, H. OLEX2: a complete structure solution, refinement and analysis program. J. Appl. Cryst. 2009, 42, 339–341.(16) Dolomanov, O. V.; Bourhis, L. J.; Gildea, R. J.; Howard, J. A. K.; Puschmann, H. OLEX2: a complete structure solution, refinement and analysis program. J. Appl. Cryst. 2009, 42, 339–341.
-
[17]
(17) Cheng, P. C.; Kuo, P. T.; Liao, Y. H.; Xie, M. Y.; Hsu, W.; Chen, J. D. Ligand-isomerism controlled structural diversity of Zn(II) and Cd(II) coordination polymers from mixed dipyridyladipoamide and benzenedicarboxylate ligands. Cryst. Growth Des. 2013, 13, 623-632.(17) Cheng, P. C.; Kuo, P. T.; Liao, Y. H.; Xie, M. Y.; Hsu, W.; Chen, J. D. Ligand-isomerism controlled structural diversity of Zn(II) and Cd(II) coordination polymers from mixed dipyridyladipoamide and benzenedicarboxylate ligands. Cryst. Growth Des. 2013, 13, 623-632.
-
[18]
(18) Li, S. X.; Liao, B. L.; Yang, G. G.; Jiang, Y. M. Synthesis and crystal structure of complex [Cd·(C7H6N2O4S)·(C10H8N4)]·2H2O. Synth. React. Inorg. M. 2015, 45, 926–929.(18) Li, S. X.; Liao, B. L.; Yang, G. G.; Jiang, Y. M. Synthesis and crystal structure of complex [Cd·(C7H6N2O4S)·(C10H8N4)]·2H2O. Synth. React. Inorg. M. 2015, 45, 926–929.
-
[19]
(19) Yin, P. X.; Cheng, J. K.; Li, Z. J.; Zhang, L.; Qin, Y. Y.; Zhang, J.; Yao, Y. G. Ag(I)-mediated in situ dehydrogenative coupling of 3-amino-1,2,4-triazole into 3,3'-azobis(1,2,4-triazole) in Cd(II) coordination polymers. Inorg. Chem. 2009, 48, 10859–10861.(19) Yin, P. X.; Cheng, J. K.; Li, Z. J.; Zhang, L.; Qin, Y. Y.; Zhang, J.; Yao, Y. G. Ag(I)-mediated in situ dehydrogenative coupling of 3-amino-1,2,4-triazole into 3,3'-azobis(1,2,4-triazole) in Cd(II) coordination polymers. Inorg. Chem. 2009, 48, 10859–10861.
-
[20]
(20) Tao, J.; Tong, M. L.; Shi, J. X.; Chen, X. M.; Ng, S. W. Blue photoluminescent zinc coordination polymers with supertetranulear cores. Chem. Commun. 2000, 2043–2044.(20) Tao, J.; Tong, M. L.; Shi, J. X.; Chen, X. M.; Ng, S. W. Blue photoluminescent zinc coordination polymers with supertetranulear cores. Chem. Commun. 2000, 2043–2044.
-
[21]
(21) Wang, Y. F.; Sun, X. Y.; Geng, J. L. Synthesis, crystal structure and fluorescent properties of a cadmium(II) complex with 3-(pyridin-4-yl)-5- (pyrazin-2-yl)-1H-1,2,4-triazole. Chin. J. Struct. Chem. 2016, 35, 397–403.(21) Wang, Y. F.; Sun, X. Y.; Geng, J. L. Synthesis, crystal structure and fluorescent properties of a cadmium(II) complex with 3-(pyridin-4-yl)-5- (pyrazin-2-yl)-1H-1,2,4-triazole. Chin. J. Struct. Chem. 2016, 35, 397–403.
-
[22]
(22) Chen, Z. F.; Gu, Y. Q.; Song, X. Y.; Liu, Y. C.; Peng, Y.; Liang, H. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8-quinolinolato-lanthanides. Euro. J. Med. Chem. 2013, 59, 194–202.(22) Chen, Z. F.; Gu, Y. Q.; Song, X. Y.; Liu, Y. C.; Peng, Y.; Liang, H. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8-quinolinolato-lanthanides. Euro. J. Med. Chem. 2013, 59, 194–202.
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