Citation: Shu-Hua CAO, Xi-Shi TAI, Chun-Ling XIN. Synthesis, Crystal Structure and Antitumor Activity of a Ca(II) Coordination Polymer Based on 4-Acetylphenoxyacetate Ligands[J]. Chinese Journal of Structural Chemistry, ;2021, 40(3): 324-328. doi: 10.14102/j.cnki.0254–5861.2011–2860 shu

Synthesis, Crystal Structure and Antitumor Activity of a Ca(II) Coordination Polymer Based on 4-Acetylphenoxyacetate Ligands

College of Chemistry and Chemical Engineering, Weifang University, Weifang 261061, China

Corresponding author: Xi-Shi TAI, taixishi@lzu.edu.cn
Received Date: 24 April 2020
Accepted Date: 29 June 2020

Fund Project: the National Natural Science Foundation of China 21171132the Natural Science Foundation Joint Project of Shandong Province ZR2017LB025

Figures(5)

A novel Ca(II) coordination polymer, [CaL₂(H₂O)₂]_n (1, HL = 4-acetylphenoxyacetic acid) has been synthesized with 4-acetylphenoxyacetic acid, Ca(ClO₄)₂·4H₂O and NaOH as raw materials. Complex 1 was characterized by elemental analysis and single-crystal X-ray diffraction analysis. The results show that the Ca(II) ion is eight-coordinated in a distorted triangular dodecahedral geometric configuration with six carboxylate O atoms of four L ligands and two O atoms of two coordinated water molecules. Complex 1 forms a one-dimensional chained structure by the bridging effect of carboxylate O atoms. The antitumor activity of HL ligand and complex 1 has also been investigated.
- 4-acetylphenoxyacetic acid,
- Ca(II) coordination polymer,
- synthesis,
- crystal structure,
- antitumor activity
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