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Citation: Zhiqiang Hao, Jinyue Li, Shiqi Zhang, Yujia Hou, Helue Sun. 维生素B₂促进的光催化氧化合成二苯甲酮[J]. University Chemistry, ;2026, 41(5): 350-357. doi: 10.12461/PKU.DXHX202510080 shu

维生素B₂促进的光催化氧化合成二苯甲酮

National Experimental Chemistry Teaching Center, College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, Hebei Province, China

Corresponding author: Zhiqiang Hao, Helue Sun,
Received Date: 21 October 2025
Revised Date: 26 February 2026

二苯甲酮的制备是现行本科化学实验教材中的一个重要的有机合成实验，但传统合成方法需要使用大量氧化剂，使用毒性较大的苯作为原料，以及存在操作复杂等问题。基于绿色化学发展理念，本改进实验将光催化合成技术引入至二苯甲酮制备的实验当中，以维生素B₂ (核黄素)作为光催化剂，利用空气中的氧气作为氧化剂，在可见光照射下催化二苯甲烷氧化制备二苯甲酮。该改进方法无需金属催化剂，反应条件温和，操作简单，成本低廉，将光化学合成的前沿理念和技术融入本科生实验教学中，为本科实验教学提供了一种安全高效、创新环保的实验案例。这不仅促进了学生对光催化反应和绿色化学的理解，也有助于学生创新能力的培养和科学思维的引导。
- Photocatalytic oxidation,
- Vitamin B₂,
- Benzophenone,
- Green chemistry
1. [1]
2. [2]
  K. Surana, B. Chaudhary, M. Diwaker, S. Sharma, Med. Chem. Commun. 2018, 9 (11), 1803.
3. [3]
4. [4]
5. [5]
  L. Buglioni, F. Raymenants, A. Slattery, S.D.A. Zondag, T. Noël, Chem. Rev. 2021, 122 (2), 2752.
6. [6]
  R. Arora, P. Samokhin, M. Lautens, Angew. Chem. Int. Ed. 2025, 64 (15), e202500929.
7. [7]
8. [8]
  J.B. Metternich, R. Gilmour, J. Am. Chem. Soc. 2015, 137 (35), 11254.
9. [9]
  W. Zhang, K.L. Carpenter, S. Lin, Angew. Chem. Int. Ed. 2020, 59 (1), 409.
10. [10]
  R. Martinez-Haya, M.A. Miranda, M.L. Marin, Eur. J. Org. Chem. 2017, 2017 (15), 2164.
11. [11]
  J. Zelenka, E. Svobodová, J. Tarábek, I. Hoskovcová, V. Boguschová, S. Bailly, M. Sikorski, J. Roithová, R. Cibulka, Org. Lett. 2019, 21 (1), 114.
12. [12]
  S. Kong, R. Liu, Z. Hao, Z. Han, G.-L. Lu, J. Lin, J. Mol. Struct. 2024, 1296, 136870.
1. [1]
  Liangzhen Hu , Li Ni , Ziyi Liu , Xiaohui Zhang , Bo Qin , Yan Xiong . A Green Chemistry Experiment on Electrochemical Synthesis of Benzophenone. University Chemistry, 2024, 39(6): 350-356. doi: 10.3866/PKU.DXHX202312001
2. [2]
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维生素B₂促进的光催化氧化合成二苯甲酮