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Citation: Rong Yuan, Jun Xu, Yuxin Wang, Wanmei Li. 皮肤科的“战痘”日记：从油脂叛乱到科学镇压[J]. University Chemistry, ;2026, 41(9): 250-256. doi: 10.12461/PKU.DXHX202508102 shu

皮肤科的“战痘”日记：从油脂叛乱到科学镇压

College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121, Zhejiang Province, China

Corresponding author: Wanmei Li, liwanmei@hznu.edu.cn
Received Date: 31 August 2025
Revised Date: 20 November 2025

以皮肤科诊室为背景，梅医生与徒弟小窦的对话为主线，揭示痤疮(痘痘)的形成机制：雄激素刺激皮脂腺过度分泌油脂，与角质细胞混合堵塞毛囊形成闭口/黑头(氧化后呈脂褐素沉积)，缺氧环境下痤疮丙酸杆菌分解油脂引发炎症，导致红肿脓疱。中医通过长痘部位判断内因——额眉鼻根对应肺热心火，口周面颊提示脾胃湿热，面颊下巴反映肝气不畅。治疗推荐水杨酸：其脂溶性可溶解角质疏通毛孔，抑制皮脂腺活性及致病菌繁殖，兼具抗炎和促进表皮更新功能。故事通过生理病理与生活干预结合，传递科学护肤理念。
- Acne pathogenesis,
- Salicylic acid treatment,
- Evidence-based dermatology
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