Citation: Junyuan Zhang, Xiangzheng Ren, Zhiwei Miao. 烯烃1,3-双官能团化反应研究进展[J]. University Chemistry, ;2026, 41(8): 148-161. doi: 10.12461/PKU.DXHX202507121 shu

烯烃1,3-双官能团化反应研究进展

1.
State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China;
2.
CHAHO (Tianjin) Technology CO., LTD, Tianjin 300400, China

Corresponding author: Zhiwei Miao, miaozhiwei@nankai.edu.cn
Received Date: 28 July 2025
Accepted Date: 15 October 2025

烯烃1,3-双官能团化反应通过在非相邻碳位点(α,γ)同步引入两个官能团，为复杂分子的构建提供了高效合成策略。该反应面临潜在反应位点增多、位点间距增大、1,2-与1,1-双官能团化产物的区域选择性竞争，以及多组分反应中的化学选择性等问题。通过多种催化反应策略，发展具有高区域选择性、步骤经济性和原子经济性的烯烃1,3-双官能团化反应是有机化学家关注的研究重点。本文综述了近年来烯烃1,3-双官能团化反应的研究进展，并对该领域的未来发展方向进行了展望。
- Alkenes,
- 1,3-Difunctionalization,
- Regioselectivity,
- Research progress
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沈阳化工大学材料科学与工程学院沈阳 110142