磁热特工队战记

引用本文: 李玉洁, 刘佳玉, 刘文博, 张廷斌, 沈康宇, 罗佳, 和媛, 彭明丽, 刘晓丽, 樊海明. 磁热特工队战记[J]. 大学化学, 2026, 41(7): 219-226. doi: 10.12461/PKU.DXHX202506067 shu

Citation: Yujie Li, Jiayu Liu, Wenbo Liu, Tingbin Zhang, Kangyu Shen, Jia Luo, Yuan He, Mingli Peng, Xiaoli Liu, Haiming Fan. The magnetothermal strike team: chronicles of the cancer war[J]. University Chemistry, 2026, 41(7): 219-226. doi: 10.12461/PKU.DXHX202506067 shu

磁热特工队战记

李玉洁 ^1, ,
刘佳玉 ^1, ,
刘文博 ^2, ,
张廷斌 ^3, ,
沈康宇 ^1, ,
罗佳 ^1, ,
和媛 ^1, ,
彭明丽 ^{1,
,} ,
刘晓丽 ^{4,
,} ,
樊海明 ^{1,
,}

1.
西北大学化学与材料科学学院, 陕西西安 710127;
2.
西北大学文学院, 陕西西安 710127;
3.
河北工业大学生命科学与健康工程学院, 天津 300131;
4.
西安交通大学精准外科与再生医学国家地方联合工程研究中心, 陕西西安 710061

通讯作者: 彭明丽,Email:mlpeng@nwu.edu.cn; 刘晓丽,Email:liuxiaoli0108@xjtu.edu.cn; 樊海明,Email:fanhm@nwu.edu.cn

基金项目:
国家自然科学基金面上项目(82472108,22072115)

西北大学本科人才培养建设项目(XM05232381)

陕西省自然科学基金重点研发项目(2024SF-YBXM-408)

国家自然科学基金优秀青年科学基金项目(82322039)

摘要: 在人类与癌症对抗中，近年来涡旋磁氧化铁纳米环以其卓越的磁热性能与灵活可调的表面功能化设计，联合铁死亡机制和免疫疗法等，成为实现多维立体抗癌策略的新一代“精兵”。本文以一场抗癌热战为切入点，介绍这种微小却强大的纳米环在交变磁场中展现出的超高比吸收率和表面功能化设计，不仅实现了对肿瘤细胞精准靶向识别，而且还能快速释放热能将其摧毁。通过这场热与免疫协同的战斗，希望向读者介绍磁性纳米材料在肿瘤磁热疗方面的知识，并激发大众对创新抗癌路径的探索热情。

关键词:

English

The magnetothermal strike team: chronicles of the cancer war

Yujie Li ^1, ,
Jiayu Liu ^1, ,
Wenbo Liu ^2, ,
Tingbin Zhang ^3, ,
Kangyu Shen ^1, ,
Jia Luo ^1, ,
Yuan He ^1, ,
Mingli Peng ^{1,
,} ,
Xiaoli Liu ^{4,
,} ,
Haiming Fan ^{1,
,}

1.
College of Chemistry and Materials Science, Northwest University, Xi'an 710127, Shaanxi Province, China;
2.
Faculty of Liberal Arts, Northwest University, Xi'an 710127, Shaanxi Province, China;
3.
School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300131, China;
4.
National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China

Corresponding author: Mingli Peng, ; Xiaoli Liu, ; Haiming Fan,

Received Date: 15 June 2025
Revised Date: 29 August 2025
Available Online: 16 March 2026

Abstract: In humanity’s protracted battle against cancer, ferrimagnetic vortex iron oxide nanorings have recently emerged as a new generation of “precision troops” in anticancer strategies. These nanostructures combine exceptional magnetothermal properties with tunable surface functionalization, working synergistically with ferroptosis mechanisms and immunotherapy to enable multidimensional anticancer approaches. Using the metaphor of a thermal warfare campaign, this article elucidates how these diminutive yet potent nanorings demonstrate ultrahigh specific absorption rates under alternating magnetic fields while achieving precise tumor targeting through sophisticated surface design. Their capacity for rapid thermal energy release enables effective tumor destruction. Through this narrative of combined thermal and immunological warfare, we aim to introduce readers to magnetic nanomaterials in tumor hyperthermia applications and stimulate interest in innovative anticancer approaches.

Key words:

Ferrimagnetic vortex iron oxide nanorings
/ Cancer therapy
/ Magnetic hyperthermia
/ Ferroptosis
/ Immunological effects

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

磁热特工队战记

通讯作者: 彭明丽,Email:mlpeng@nwu.edu.cn; 刘晓丽,Email:liuxiaoli0108@xjtu.edu.cn; 樊海明,Email:fanhm@nwu.edu.cn

English

The magnetothermal strike team: chronicles of the cancer war

Corresponding author: Mingli Peng, ; Xiaoli Liu, ; Haiming Fan,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

磁热特工队战记

通讯作者: 彭明丽,Email:mlpeng@nwu.edu.cn; 刘晓丽,Email:liuxiaoli0108@xjtu.edu.cn; 樊海明,Email:fanhm@nwu.edu.cn

English

The magnetothermal strike team: chronicles of the cancer war

Corresponding author: Mingli Peng, ; Xiaoli Liu, ; Haiming Fan,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

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