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Citation: Zhi Zheng, Feiyang Liu, Junlong Zhao. D-Amino Acids and Mirror-Image Proteins[J]. University Chemistry, ;2026, 41(2): 353-359. doi: 10.12461/PKU.DXHX202505017 shu

D-Amino Acids and Mirror-Image Proteins

1.
National Chemistry Experimental Teaching Demonstration Center, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China;
2.
School of Medicine, Northwest University, Xi'an 710069, China

Corresponding author: Junlong Zhao, zhaojunlong327@163.com
Received Date: 8 May 2025
Revised Date: 22 May 2025

Mirror-image proteins, composed of D-amino acids and glycine, exhibit distinct structures and functions compared to natural proteins. Starting from the homochirality hypothesis of life’s origin, this article introduces synthetic methods and applications of mirror-image amino acids and proteins. While highlighting their positive societal impacts, we also address potential risks of mirror-image life, aiming to provide a balanced view on this technology’s development.
- Mirror-image proteins,
- D-amino acids,
- Homochirality,
- Mirror-image life
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