悟空遇“妖”解迷津，液金施术救苍生

引用本文: 张梦莹, 费代强, 刘晓倩, 孙小敏, 白宇, 王宇, 吕查德, 齐殿鹏, 王磊. 悟空遇“妖”解迷津，液金施术救苍生[J]. 大学化学, 2026, 41(7): 154-160. doi: 10.12461/PKU.DXHX202504080 shu

Citation: Mengying Zhang, Daiqiang Fei, Xiaoqian Liu, Xiaomin Sun, Yu Bai, Yu Wang, Chade Lv, Dianpeng Qi, Lei Wang. The fabrication of liquid-metal-based micro/nano robots and their biomedical applications[J]. University Chemistry, 2026, 41(7): 154-160. doi: 10.12461/PKU.DXHX202504080 shu

悟空遇“妖”解迷津，液金施术救苍生

张梦莹 ^1, ,
费代强 ^2, ,
刘晓倩 ^1, ,
孙小敏 ^1, ,
白宇 ^3, ,
王宇 ^1, ,
吕查德 ^{1,
,} ,
齐殿鹏 ^{1,
,} ,
王磊 ^{1,
,}

1.
哈尔滨工业大学化工与化学学院, 黑龙江哈尔滨 150001;
2.
哈尔滨工业大学数学学院, 黑龙江哈尔滨 150001;
3.
黑龙江中医药大学, 黑龙江哈尔滨 150040

通讯作者: 吕查德,Email:lv.chade@hit.edu.cn; 齐殿鹏,Email:dpqi@hit.edu.cn; 王磊,Email:leiwang_chem@hit.edu.cn

基金项目:
黑龙江省自然科学基金优秀青年基金(YQ2022E021)

国家自然科学基金(52473109,52073071)

黑龙江省高等教育教学改革研究项目(SJGYY2024002,SJGDB2024001)

黑龙江省龙江学者支持计划(王磊)

摘要: 肿瘤疾病在人们日常生活中难以避免且难以治愈。而随着现代生物纳米技术的发展，科学家们设计出了一类智能微纳米材料——液态金属机器人。液态金属机器人是基于生物技术、材料科学、微纳米技术、机械学等多学科交叉的新兴研究领域。由于其体型微小，可以在外场的控制下发生各种各样的形变，使其能够靶向治疗癌细胞，但该技术还并未广为人知。本文基于四大名著之一——《西游记》，以拟人化的手法讲述了液态金属机器人的制备方法、变形特点及体内治疗过程，以期促进广大读者对液态金属机器人科学机理的了解，为实现该技术的实际应用奠定基础。

关键词:

English

The fabrication of liquid-metal-based micro/nano robots and their biomedical applications

Mengying Zhang ^1, ,
Daiqiang Fei ^2, ,
Xiaoqian Liu ^1, ,
Xiaomin Sun ^1, ,
Yu Bai ^3, ,
Yu Wang ^1, ,
Chade Lv ^{1,
,} ,
Dianpeng Qi ^{1,
,} ,
Lei Wang ^{1,
,}

1.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, Heilongjiang Province, China;
2.
School of Mathematics, Harbin Institute of Technology, Harbin 150001, Heilongjiang Province, China;
3.
Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang Province, China

Corresponding author: Chade Lv, ; Dianpeng Qi, ; Lei Wang,

Received Date: 28 April 2025
Revised Date: 29 August 2025
Available Online: 26 January 2026

Abstract: Cancer remains a prevalent and challenging disease in modern society. With recent advancements in bionanotechnology, researchers have developed intelligent micro/nanomaterials known as liquid-metal-based robots. This emerging interdisciplinary technology combines biotechnology, materials science, nanoengineering, and mechanical systems. These miniature robots can undergo controlled morphological transformations under external fields, enabling targeted cancer therapy, though the technology remains relatively unknown. Drawing inspiration from the literary classic “Journey to the West”, this study employs anthropomorphic narrative techniques to elucidate the fabrication methods, deformation characteristics, and therapeutic processes of liquid-metal robots in vivo. This article aims to enhance public understanding of the scientific principles underlying these transformative biomedical agents, thereby facilitating their practical clinical applications.

Key words:

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

悟空遇“妖”解迷津，液金施术救苍生

通讯作者: 吕查德,Email:lv.chade@hit.edu.cn; 齐殿鹏,Email:dpqi@hit.edu.cn; 王磊,Email:leiwang_chem@hit.edu.cn

English

The fabrication of liquid-metal-based micro/nano robots and their biomedical applications

Corresponding author: Chade Lv, ; Dianpeng Qi, ; Lei Wang,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

悟空遇“妖”解迷津，液金施术救苍生

通讯作者: 吕查德,Email:lv.chade@hit.edu.cn; 齐殿鹏,Email:dpqi@hit.edu.cn; 王磊,Email:leiwang_chem@hit.edu.cn

English

The fabrication of liquid-metal-based micro/nano robots and their biomedical applications

Corresponding author: Chade Lv, ; Dianpeng Qi, ; Lei Wang,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

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